UniProt functional annotation for P46422

UniProt code: P46422.

Organism: Arabidopsis thaliana (Mouse-ear cress).
Taxonomy: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliophyta; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
 
Function: Binds auxin, endogenous flavonoids and the phytoalexin camalexin and may be involved in regulating the binding and transport of small bioactive natural products and defense-related compounds during plant stress. Binds a series of heterocyclic compounds, including lumichrome, harmane, norharmane and indole-3- aldehyde. In vitro, possesses glutathione S-transferase activity toward 1-chloro-2,4-dinitrobenzene (CDNB) and benzyl isothiocyanate (BITC). Acts as glutathione peroxidase on cumene hydroperoxide, linoleic acid-13-hydroperoxide and trans-stilbene oxide, but not trans-cinnamic acid or IAA-CoA.
 
Catalytic activity: RX + glutathione = HX + R-S-glutathione.
Subunit: Homodimer.
Subcellular location: Cytoplasm, cytosol. Microsome. Endoplasmic reticulum. Note=Plasma membrane vesicles.
Tissue specificity: Expressed in the root-shoot transition zone and root tips.
Induction: By ethylene, auxin, glutathione, salicylic acid, copper, paraquat, acetochlor, metolachlor and the pathogens P.syringae and Hyaloperonospora parasitica.
Similarity: Belongs to the GST superfamily. Phi family.
Similarity: Contains 1 GST C-terminal domain.
Similarity: Contains 1 GST N-terminal domain.

Annotations taken from UniProtKB at the EBI.