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PDBsum entry 1gjo
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Contents |
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* Residue conservation analysis
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PDB id:
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Transferase
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Title:
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The fgfr2 tyrosine kinase domain
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Structure:
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Fibroblast growth factor receptor 2. Chain: a. Fragment: tyrosine kinase domain residues 465-768. Synonym: fgfr-2, keratinocyte. Engineered: yes
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Source:
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Homo sapiens. Human. Organism_taxid: 9606. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108.
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Biol. unit:
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Tetramer (from PDB file)
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Resolution:
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2.40Å
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R-factor:
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0.214
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R-free:
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0.256
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Authors:
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T.A.Ceska,R.Owens,C.Doyle,P.Hamlyn,T.Crabbe,D.Moffat,J.Davis, R.Martin,M.J.Perry
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Key ref:
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T.A.Ceska
et al.
The fgfr2 tyrosine kinase domain.
To be published,
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Date:
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31-Jul-01
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Release date:
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15-Aug-03
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PROCHECK
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Headers
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References
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P21802
(FGFR2_HUMAN) -
Fibroblast growth factor receptor 2 from Homo sapiens
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Seq:
Struc:
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821 a.a.
280 a.a.
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Key: |
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PfamA domain |
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Secondary structure |
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CATH domain |
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Enzyme class:
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E.C.2.7.10.1
- receptor protein-tyrosine kinase.
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Reaction:
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L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H+
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L-tyrosyl-[protein]
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+
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ATP
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=
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O-phospho-L-tyrosyl-[protein]
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+
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ADP
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+
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H(+)
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Molecule diagrams generated from .mol files obtained from the
KEGG ftp site
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Links
