UniProt functional annotation for P00864

UniProt code: P00864.

Organism: Escherichia coli (strain K12).
Taxonomy: Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia.
 
Function: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
 
Catalytic activity: Phosphate + oxaloacetate = H(2)O + phosphoenolpyruvate + HCO(3)(-).
Cofactor: Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence={ECO:0000250};
Enzyme regulation: The enzyme has distinct binding sites for each of the allosteric effectors such as acetyl-CoA, fructose 1,6- bisphosphate, guanosine 3'-diphosphate 5'-diphosphate, long chain fatty acids, and L-aspartate.
Subunit: Homotetramer.
Similarity: Belongs to the PEPCase type 1 family. {ECO:0000305}.

Annotations taken from UniProtKB at the EBI.