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PDBsum entry 1ex0

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Top Page protein ligands metals Protein-protein interface(s) links
Protein chain A    -    representing identical chain: B PDB id
1ex0
Protein chain A highlighted
(click to view)
 
Jmol
Motifs
Secondary structure
Wiring diagram
Residue conservation
ProMotif
10 sheets
1 beta alpha beta unit
14 beta hairpins
17 beta bulges
38 strands
15 helices
12 helix-helix interacs
59 beta turns
6 gamma turns
Catalytic residues
D396-C314-H373-Y560
Variants
Gly592Ser
Tyr204Phe
Phe53Ile
Thr550Ile
Leu588Gln
Ala132Ser
Ala394Val
Val650Ile
Arg684Gln
  
Chain & (705 residues)

UniProt code: P00488 (F13A_HUMAN)   [Pfam]   [Ensembl gene]

structural classification (4 domains) :
Domain Links CATH no.   Class Architecture
1 2.60.40.10 = Mainly Beta Sandwich
2 3.90.260.10 = Alpha Beta Alpha-Beta Complex
3 2.60.40.10 = Mainly Beta Sandwich
4 2.60.40.10 = Mainly Beta Sandwich

Key:  
Sec. struc: Helices labelled H1, H2, ... and strands by their sheets A, B, ...
  Helix Strand  
Motifs:   
    beta turn     gamma turn     beta hairpin
CSA annotation:   
    catalytic residue
Human variant:   
    variant residue
Residue contacts:   
    to ligand     to metal
PDB SITE records:   
 AC1  AC2  AC3  AC4  AC5
 AC6  AC7  AC8  AC9  BC1
 BC2

Jmol
RasMol

FASTA
file
Domain 1
Topology diagram


Hera


Domain 2
Topology diagram


Hera


Domain 3
Topology diagram


Hera


Domain 4
Topology diagram


Hera


  Analysis of sequence's residue conservation
  Related protein sequences in the PDB
  
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