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UniProt functional annotation for Q02724 | ||
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| UniProt code: Q02724. |
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| Organism: | |
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). |
| Taxonomy: | |
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces. |
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| Function: | |
Protease that catalyzes two essential functions in the SUMO pathway: processing of full-length SMT3 to its mature form and deconjugation of SMT3 from targeted proteins. Has an essential role in the G2/M phase of the cell cycle. {ECO:0000269|PubMed:10094048}. |
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| Catalytic activity: | |
Reaction=Hydrolysis of the alpha-linked peptide bond in the sequence Gly-Gly-|-Ala-Thr-Tyr at the C-terminal end of the small ubiquitin- like modifier (SUMO) propeptide, Smt3, leading to the mature form of the protein. A second reaction involves the cleavage of an epsilon- linked peptide bond between the C-terminal glycine of the mature SUMO and the lysine epsilon-amino group of the target protein.; EC=3.4.22.68; Evidence={ECO:0000269|PubMed:10882122}; |
| Miscellaneous: | |
Present with 377 molecules/cell in log phase SD medium. {ECO:0000269|PubMed:14562106}. |
| Similarity: | |
Belongs to the peptidase C48 family. {ECO:0000305}. |
Annotations taken from UniProtKB at the EBI.