UniProt functional annotation for Q7LYW7

UniProt code: Q7LYW7.

Organism: Thermococcus litoralis (strain ATCC 51850 / DSM 5473 / JCM 8560 / NS-C).
Taxonomy: Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae; Thermococcus.
 
Function: Part of the ABC transporter complex MalEFGK involved in trehalose/maltose import. Binds maltose and trehalose. {ECO:0000269|PubMed:11453995, ECO:0000269|PubMed:16532450, ECO:0000269|PubMed:8759837, ECO:0000269|PubMed:9457875}.
 
Subunit: The complex is composed of two ATP-binding proteins (MalK), two transmembrane proteins (MalG and MalF) and a solute-binding protein (MalE). {ECO:0000269|PubMed:11453995}.
Subcellular location: Cell membrane {ECO:0000305|PubMed:11453995, ECO:0000305|PubMed:9457875}; Lipid-anchor {ECO:0000305|PubMed:11453995, ECO:0000305|PubMed:9457875}.
Ptm: Glycosylated. {ECO:0000269|PubMed:11453995}.
Miscellaneous: The protein assumes different conformations with different physical properties depending whether maltose or trehalose is bound to the protein. {ECO:0000305|PubMed:16532450}.
Similarity: Belongs to the bacterial solute-binding protein 1 family. {ECO:0000305}.

Annotations taken from UniProtKB at the EBI.