PDBsum entry 1e3o

Transcription

PDB id: 1e3o

Contents

Protein chain

132 a.a. *

DNA/RNA

Waters ×138

* Residue conservation analysis

PDB id:

1e3o

Name:

Transcription

Title:

Crystal structure of oct-1 pou dimer bound to more

Structure:

5'-d( Ap Tp Gp Cp Ap Tp Gp Ap Gp Gp A)-3'. Chain: a. Engineered: yes. 5'-d( Tp Cp Cp Tp Cp Ap Tp Gp Cp Ap T)-3'. Chain: b. Engineered: yes. Octamer-binding transcription factor 1. Chain: c. Fragment: DNA-binding domain.

Source:

Synthetic: yes. Homo sapiens. Human. Organism_taxid: 9606. Cellular_location: nucleus. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Other_details: the protein was expressed in e.Coli by recombinant DNA technology

Biol. unit:

Hexamer (from PDB file)

Resolution:

1.90Å R-factor: 0.220 R-free: 0.242

Authors:

A.Remenyi,A.Tomilin,E.Pohl,H.Schoeler,M.Wilmanns

Date:

20-Jun-00 Release date: 10-Nov-01

Protein chain

P14859  (PO2F1_HUMAN) -  POU domain, class 2, transcription factor 1 from Homo sapiens

Seq: 743 a.a.

Struc: 132 a.a.*

* PDB and UniProt seqs differ at 6 residue positions (black crosses)

DNA/RNA chains

A-T-G-C-A-T-G-A-G-G-A 11 bases

T-C-C-T-C-A-T-G-C-A-T 11 bases