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UniProt functional annotation for Q61830 | ||
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| UniProt code: Q61830. |
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| Organism: | |
Mus musculus (Mouse). |
| Taxonomy: | |
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus. |
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| Function: | |
Mediates the endocytosis of glycoproteins by macrophages. Binds both sulfated and non-sulfated polysaccharide chains. Acts as phagocytic receptor for bacteria, fungi and other pathogens. {ECO:0000269|PubMed:1421407}. |
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| Subcellular location: | |
Endosome membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Cell membrane {ECO:0000250}; Single- pass type I membrane protein {ECO:0000250}. |
| Tissue specificity: | |
Detected in macrophages. {ECO:0000269|PubMed:1421407}. |
| Induction: | |
Down-regulated by interferon gamma. {ECO:0000269|PubMed:1421407}. |
Annotations taken from UniProtKB at the EBI.