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UniProt functional annotation for P23256 | ||
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| UniProt code: P23256. |
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| Organism: | |
Escherichia coli (strain K12). |
| Taxonomy: | |
Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia. |
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| Function: | |
Acts as a beta-cystathionase and as a repressor of the maltose regulon. |
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| Catalytic activity: | |
Reaction=H2O + L,L-cystathionine = L-homocysteine + NH4(+) + pyruvate; Xref=Rhea:RHEA:13965, ChEBI:CHEBI:15361, ChEBI:CHEBI:15377, ChEBI:CHEBI:28938, ChEBI:CHEBI:58161, ChEBI:CHEBI:58199; Evidence={ECO:0000269|PubMed:7665481}; |
| Catalytic activity: | |
Reaction=an S-substituted L-cysteine + H2O = a thiol + NH4(+) + pyruvate; Xref=Rhea:RHEA:18121, ChEBI:CHEBI:15361, ChEBI:CHEBI:15377, ChEBI:CHEBI:28938, ChEBI:CHEBI:29256, ChEBI:CHEBI:58717; EC=4.4.1.13; Evidence={ECO:0000269|PubMed:7665481}; |
| Cofactor: | |
Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326; Evidence={ECO:0000269|PubMed:10698925, ECO:0000269|PubMed:7665481}; |
| Subunit: | |
Homodimer. Interacts with MalT. {ECO:0000269|PubMed:10698925}. |
| Similarity: | |
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. MalY/PatB cystathionine beta-lyase subfamily. {ECO:0000305}. |
Annotations taken from UniProtKB at the EBI.