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UniProt functional annotation for P00509 | ||
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| UniProt code: P00509. |
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| Organism: | |
Escherichia coli (strain K12). |
| Taxonomy: | |
Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia. |
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| Catalytic activity: | |
Reaction=2-oxoglutarate + L-aspartate = L-glutamate + oxaloacetate; Xref=Rhea:RHEA:21824, ChEBI:CHEBI:16452, ChEBI:CHEBI:16810, ChEBI:CHEBI:29985, ChEBI:CHEBI:29991; EC=2.6.1.1; Evidence={ECO:0000269|PubMed:10556573}; |
| Cofactor: | |
Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326; Evidence={ECO:0000269|PubMed:11148029}; |
| Subunit: | |
Homodimer. {ECO:0000269|PubMed:17713924}. |
| Subcellular location: | |
Cytoplasm. |
| Induction: | |
Transcription is increased specifically in response to 2,4,6-trinitrotoluene (TNT) and its indicator compounds 1,3-DNB, 2,4- DNT, and 2,6-DNT. {ECO:0000269|PubMed:25561288}. |
| Biotechnology: | |
Has been used to construct a 2,4,6-trinitrotoluene (TNT) biosensor strain. {ECO:0000269|PubMed:25561288}. |
| Similarity: | |
Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. {ECO:0000305}. |
Annotations taken from UniProtKB at the EBI.