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UniProt functional annotation for P39476 | ||
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| UniProt code: P39476. |
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| Organism: | |
Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) (Sulfolobus solfataricus). |
| Taxonomy: | |
Archaea; Crenarchaeota; Thermoprotei; Sulfolobales; Sulfolobaceae; Saccharolobus. |
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| Function: | |
Can constrain negative DNA supercoils. May be involved in maintaining the integrity of the genome at high temperature (By similarity). Stimulates the Holliday junction cleavage activity of Hjc (PubMed:11709558). {ECO:0000250|UniProtKB:P61990, ECO:0000269|PubMed:11709558}. |
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| Biophysicochemical properties: | |
pH dependence: Highly stable from pH 0 to pH 12. {ECO:0000269|PubMed:27853299}; Temperature dependence: Hyperthermostable. {ECO:0000269|PubMed:27853299}; |
| Subunit: | |
Monomer. {ECO:0000269|PubMed:27853299, ECO:0000269|PubMed:3132977, ECO:0000269|PubMed:7634092}. |
| Subcellular location: | |
Cytoplasm {ECO:0000269|PubMed:27853299}. |
| Similarity: | |
Belongs to the 7 kDa DNA-binding/endoribonuclease P2 family. {ECO:0000305}. |
| Sequence caution: | |
Sequence=AAK42679.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305}; |
Annotations taken from UniProtKB at the EBI.