spacer
spacer

Ligand clusters for UniProt code P00918

Ligand clusters for P00918: Carbonic anhydrase 2 OS=Homo sapiens GN=CA2 PE=1 SV=2

Top 6 (of 28) ligand clusters
Cluster 1.
316 ligand types
1222 ligands
Cluster 2.
7 ligand types
87 ligands
Cluster 3.
4 ligand types
19 ligands
Cluster 4.
4 ligand types
5 ligands
Cluster 5.
3 ligand types
9 ligands
Cluster 6.
3 ligand types
3 ligands
Representative protein: 2fouA  
 

Structures

PDB   Schematic diagram
2fouA    
4pq7A    
1if9A    
1i8zA    
3f4xA    
 more ...

 

 Cluster 1 contains 316 ligand types (of which only 20 are listed. Click for all)

Use checkboxes to select ligands to display in RasMol, Jmol, or download as an SDF file.
Selection shortcuts: select all/none invert selection.
Ligand Description


 
1. Ligand: BCT × 2
Bicarbonate ion
PDB codes: 1bic(A), 1lgd(A).

_Zn
 
2. Metal: _ZN × 473
PDB codes: 12ca(A), 1a42(A), 1am6(A), 1avn(A), 1bcd(A), 1bic(A), 1bn1(A), 1bn3(A), 1bn4(A), 1bnm(A), 1bnn(A), 1bnq(A), 1bnt(A), 1bnu(A), 1bnv(A), 1bnw(A), 1bv3(A), 1ca2(A), 1ca3(A), 1cai(A), 1caj(A), 1cak(A), 1cal(A), 1cam(A), 1cay(A), 1caz(A), 1ccs(A), 1cct(A), 1ccu(A), 1cil(A), 1cim(A), 1cin(A), 1cnc(A), 1cng(A), 1cnh(A), 1cni(A), 1cnj(A), 1cnk(A), 1cnw(A), 1cnx(A), 1cny(A), 1cva(A), 1cvb(A), 1cvc(A), 1cvd(A), 1cve(A), 1cvh(A), 1dca(A), 1dcb(A), 1eou(A), 1f2w(A), 1fql(A), 1fqm(A), 1fr7(A), 1g0e(A), 1g0f(A), 1g1d(A), 1g3z(A), 1g45(A), 1g46(A), 1g48(A), 1g4j(A), 1g4o(A), 1g52(A), 1g53(A), 1g54(A), 1h4n(A), 1h9n(A), 1h9q(A), 1hca(A), 1hea(A), 1heb(A), 1hec(A), 1hed(A), 1i8z(A), 1i90(A), 1i91(A), 1i9l(A), 1i9m(A), 1i9n(A), 1i9o(A), 1i9p(A), 1i9q(A), 1if4(A), 1if5(A), 1if6(A), 1if7(A), 1if8(A), 1if9(A), 1kwq(A), 1kwr(A), 1lg5(A), 1lg6(A), 1lgd(A), 1lug(A), 1lzv(A), 1moo(A), 1mua(A), 1okl(A), 1okm(A), 1okn(A), 1oq5(A), 1ray(A), 1raz(A), 1t9n(A), 1tb0(X), 1tbt(X), 1te3(X), 1teu(X), 1tg3(A), 1tg9(A), 1th9(A), 1thk(A), 1ttm(A), 1uga(A), 1ugb(A), 1ugc(A), 1ugd(A), 1uge(A), 1ugf(A), 1ugg(A), 1xeg(A), 1xev(A), 1xpz(A), 1xq0(A), 1yda(A), 1ydb(A), 1ydc(A), 1ydd(A), 1yo0(A), 1yo1(A), 1yo2(A), 1z9y(A), 1ze8(A), 1zfk(A), 1zfq(A), 1zge(A), 1zgf(A), 1zh9(A), 1zsb(A), 1zsc(A), 2abe(A), 2aw1(A), 2ax2(A), 2ca2(A), 2cba(A), 2cbb(A), 2cbc(A), 2cbd(A), 2eu2(A), 2eu3(A), 2ez7(A), 2f14(A), 2fmg(A), 2fmz(A), 2fnk(A), 2fnm(A), 2fnn(A), 2foq(A), 2fos(A), 2fou(A), 2fov(A), 2gd8(A), 2geh(A), 2h15(A), 2h4n(A), 2hd6(A), 2hkk(A), 2hl4(A), 2hnc(A), 2hoc(A), 2ili(A), 2nng(A), 2nno(A), 2nns(A), 2nnv(A), 2nwo(A), 2nwp(A), 2nwy(A), 2nwz(A), 2nxr(A), 2nxs(A), 2nxt(A), 2o4z(A), 2osf(A), 2osm(A), 2pou(A), 2pov(A), 2pow(A), 2q1b(A), 2q1q(A), 2q38(A), 2qo8(A), 2qoa(A), 2qp6(A), 2vva(X), 2vvb(X), 2wd2(A), 2wd3(A), 2weg(A), 2weh(A), 2wej(A), 2weo(A), 2x7s(A), 2x7t(A), 2x7u(A), 3b4f(A), 3bet(A), 3bl0(A), 3bl1(A), 3c7p(A), 3ca2(A), 3caj(A), 3cyu(A), 3d8w(A), 3d92(A), 3d9z(A), 3daz(A), 3dbu(A), 3dc3(A), 3dc9(A), 3dcc(A), 3dcs(A), 3dcw(A), 3dd0(A), 3dd8(A), 3dv7(A), 3dvb(A), 3dvc(A), 3dvd(A), 3efi(A), 3eft(A), 3f4x(A), 3f8e(A), 3ffp(X), 3gz0(A), 3hfp(A), 3hkn(A), 3hkq(A), 3hkt(A), 3hku(A), 3hlj(A), 3hs4(A), 3ibi(A), 3ibl(A), 3ibn(A), 3ibu(A), 3ieo(A), 3igp(A), 3k2f(A), 3k34(A), 3k7k(A), 3kig(A), 3kkx(A), 3kne(A), 3ks3(A), 3kwa(A), 3l14(A), 3m04(A), 3m14(A), 3m1j(A), 3m1k(A), 3m1q(A), 3m1w(A), 3m2n(A), 3m2x(A), 3m2y(A), 3m2z(A), 3m3x(A), 3m40(A), 3m5e(A), 3m5s(A), 3m5t(A), 3m67(A), 3m96(A), 3m98(A), 3mhc(A), 3mhi(A), 3mhl(A), 3mhm(A), 3mho(A), 3ml2(A), 3mmf(A), 3mna(A), 3mnh(A), 3mni(A), 3mnj(A), 3mnk(A), 3mnu(A), 3mwo(A), 3myq(A), 3mzc(A), 3n0n(A), 3n2p(A), 3n3j(A), 3n4b(A), 3nb5(A), 3ni5(A), 3nj9(A), 3oik(A), 3oil(A), 3oim(A), 3oku(A), 3okv(A), 3oy0(A), 3oyq(A), 3oys(A), 3p3h(A), 3p3j(A), 3p44(A), 3p4v(A), 3p55(A), 3p58(A), 3p5a(A), 3p5l(A), 3pjj(A), 3po6(A), 3pyk(A), 3qyk(A), 3r16(A), 3r17(B), 3rg3(A), 3rg4(A), 3rge(A), 3rj7(A), 3rld(A), 3ryj(B), 3ryv(B), 3ryx(B), 3ryy(A), 3ryz(A), 3rz0(B), 3rz1(B), 3rz5(A), 3rz7(A), 3rz8(A), 3s71(B), 3s72(B), 3s73(B), 3s74(B), 3s75(B), 3s76(A), 3s77(B), 3s78(B), 3s8x(A), 3s9t(A), 3sap(A), 3sax(A), 3sbh(A), 3sbi(A), 3t5u(A), 3t5z(A), 3t82(A), 3t83(A), 3t84(A), 3t85(A), 3tmj(A), 3tvn(X), 3tvo(X), 3u3a(X), 3u45(X), 3u47(A), 3u7c(A), 3v2j(A), 3v2m(A), 3v3f(A), 3v3g(B), 3v3h(B), 3v3i(B), 3v3j(A), 3v5g(A), 3v7x(A), 3vbd(A), 3zp9(A), 4bcw(A), 4bf1(A), 4bf6(A), 4ca2(A), 4cac(A), 4cq0(A), 4dz7(A), 4dz9(A), 4e3d(A), 4e3f(A), 4e3g(A), 4e3h(A), 4e49(A), 4e4a(A), 4e5q(A), 4fik(A), 4fl7(A), 4fpt(A), 4frc(A), 4fu5(A), 4fvn(A), 4fvo(A), 4g0c(A), 4gl1(X), 4hba(A), 4hew(A), 4hey(A), 4hez(A), 4hf3(A), 4idr(X), 4ilx(A), 4ito(A), 4itp(A), 4iwz(A), 4js6(A), 4jsa(A), 4jss(A), 4jsw(A), 4jsz(A), 4k0s(A), 4k0t(A), 4k0z(A), 4k13(A), 4k1q(A), 4kap(A), 4kni(A), 4knj(A), 4kuv(A), 4kuw(A), 4kuy(A), 4kv0(A), 4l5u(A), 4l5v(A), 4l5w(A), 4lhi(A), 4lp6(A), 4m2r(A), 4m2u(A), 4m2v(A), 4m2w(A), 4mdg(A), 4mdl(A), 4mdm(A), 4mlt(A), 4mlx(A), 4mo8(A), 4mty(A), 4n0x(B), 4n16(A), 4pq7(A), 4q6d(A), 4q6e(A), 4qef(A), 4qy3(A), 4r59(A), 4r5a(A), 4r5b(A), 5ca2(A), 5cac(A), 6ca2(A), 7ca2(A), 8ca2(A), 9ca2(A).


 
3. Ligand: DMS × 21
dimethyl sulfoxide
Dimethyl sulfoxide
PDB codes: 2weo(A), 3m1j(A), 3m2n(A), 3m67(A), 3m96(A), 3mhi(A), 3mhl(A), 3mho(A), 3myq(A), 3n2p(A), 3s8x(A), 3s9t(A), 3sax(A), 3sbh(A), 3sbi(A), 4itp(A), 4k0z(A), 4kni(A), 4lhi(A), 4q6e(A).


 
4. Ligand: AZM × 12
acetazolamide
5-Acetamido-1,3,4-Thiadiazole-2-Sulfonamide
PDB codes: 1yda(A), 1ydb(A), 1ydd(A), 1zsb(A), 2h4n(A), 3dc3(A), 3hs4(A), 3v2j(A), 3v2m(A), 4g0c(A), 4k0s(A).


 
5. Ligand: ETS × 4
dorzolamide
(4s-Trans)-4-(Ethylamino)-5,6-Dihydro-6-Methyl-4h- Thieno(2,3-B)thiopyran-2-Sulfonamide-7,7-Dioxide
PDB codes: 1cil(A), 4k13(A), 4m2u(A), 4m2w(A).


 
6. Ligand: EZL × 3
ethoxzolamide
6-Ethoxy-1,3-Benzothiazole-2-Sulfonamide
PDB codes: 3caj(A), 3dcw(A), 3dd0(A).


 
7. Ligand: BZ1 × 2
brinzolamide
(+)-4-Ethylamino-3,4-Dihydro-2-(Methoxy)propyl-2h- Thieno[3,2-E]-1,2-Thiazine-6-Sulfonamide-1,1-
Dioxide
PDB codes: 4m2r(A), 4m2v(A).


 
8. Ligand: ACT × 1
acetic acid
Acetate ion
PDB code: 1xeg(A).


 
9. Ligand: ALE × 1
epinephrine
L-Epinephrine
PDB code: 2hkk(A).


 
10. Ligand: AMJ × 1
lacosamide
N~2~-Acetyl-N-Benzyl-O-Methyl-L-Serinamide
PDB code: 3ieo(A).


 
11. Ligand: BL1 × 1
indapamide
4-Chloro-N-[(2s)-2-Methyl-2,3-Dihydro-1h-Indol-1-Yl]- 3-Sulfamoylbenzamide
PDB code: 3bl1(A).


 
12. Ligand: CEL × 1
celecoxib
4-[5-(4-Methylphenyl)-3-(Trifluoromethyl)-1h-Pyrazol- 1-Yl]benzenesulfonamide
PDB code: 1oq5(A).


 
13. Ligand: DHI × 1
l-histidine
D-Histidine
PDB code: 2ez7(A).


 
14. Ligand: DPN × 1
l-phenylalanine
D-Phenylalanine
PDB code: 2fmz(A).


 
15. Ligand: FUN × 1
furosemide
5-(Aminosulfonyl)-4-Chloro-2-[(2-Furylmethyl) amino]benzoic acid
PDB code: 1z9y(A).


 
16. Ligand: HAE × 1
acetohydroxamic acid
Acetohydroxamic acid
PDB code: 1am6(A).


 
17. Ligand: I7A × 1
dichlorphenamide
4,5-Dichlorobenzene-1,3-Disulfonamide
PDB code: 2pou(A).


 
18. Ligand: KLT × 1
chlorthalidone
2-Chloro-5-[(1s)-1-Hydroxy-3-Oxo-2h-Isoindol-1- Yl]benzenesulfonamide
PDB code: 3f4x(A).


 
19. Ligand: NHY × 1
hydroxyurea
N-Hydroxyurea
PDB code: 2geh(A).


 
20. Ligand: SPM × 1
spermine
Spermine
PDB code: 3kwa(A).

 + more. Press for full list
 

 

 Cluster 2 contains 7 ligand types

Selection shortcuts: select all/none invert selection.
Ligand Description


 
1. Ligand: DMS × 56
dimethyl sulfoxide
Dimethyl sulfoxide
PDB codes: 3m2n(A), 3m3x(A), 3m40(A), 3m5e(A), 3m67(A), 3m96(A), 3m98(A), 3mhi(A), 3mhl(A), 3mhm(A), 3mho(A), 3myq(A), 3oim(A), 3oku(A), 3okv(A), 3oy0(A), 3oyq(A), 3oys(A), 3p5a(A), 3p5l(A), 3qyk(A), 3r16(A), 3r17(B), 3rj7(A), 3rz1(B), 3rz5(A), 3rz8(A), 3s72(B), 3s76(A), 3s8x(A), 3s9t(A), 3sap(A), 3sax(A), 3sbh(A), 3sbi(A), 3v2m(A), 4dz7(A), 4dz9(A), 4fpt(A), 4frc(A), 4fu5(A), 4fvn(A), 4fvo(A), 4ilx(A), 4ito(A), 4iwz(A), 4k0t(A), 4k0z(A), 4k13(A), 4kni(A), 4knj(A), 4lhi(A), 4mlt(A), 4mlx(A), 4q6d(A), 4q6e(A).


 
2. Ligand: GOL × 23
Glycerol
PDB codes: 3d92(A), 3d93(A), 3hkn(A), 3hkq(A), 3igp(A), 3ks3(A), 3nb5(A), 3po6(A), 3u3a(X), 3u45(X), 3u47(A), 3u7c(A), 3v7x(A), 4hba(A), 4l5u(A), 4l5v(A), 4l5w(A), 4mty(A), 4n16(A), 4qef(A), 4r59(A), 4r5a(A), 4r5b(A).


 
3. Ligand: BME × 4
Beta-Mercaptoethanol
PDB codes: 4kuv(A), 4kuw(A), 4kuy(A), 4kv0(A).


 
4. Ligand: 4MZ × 1
4-Methylimidazole
PDB code: 4hey(A).


 
5. Ligand: A09 × 1
N-Hydroxybenzenesulfonamide
PDB code: 3t5u(A).


 
6. Ligand: IMD × 1
Imidazole
PDB code: 4hf3(A).


 
7. Ligand: SO4 × 1
Sulfate ion
PDB code: 3pyk(A).

 

 Cluster 3 contains 4 ligand types

Selection shortcuts: select all/none invert selection.
Ligand Description


 
1. Ligand: AZM × 1
acetazolamide
5-Acetamido-1,3,4-Thiadiazole-2-Sulfonamide
PDB code: 3hs4(A).


 
2. Ligand: BCN × 9
Bicine
PDB codes: 3m2n(A), 3s8x(A), 3s9t(A), 3sap(A), 3sax(A), 3sbh(A), 3sbi(A), 4q6d(A), 4q6e(A).


 
3. Ligand: GOL × 6
Glycerol
PDB codes: 2vva(X), 2vvb(X), 3v7x(A), 3vbd(A), 4k0t(A), 4n16(A).


 
4. Ligand: SO4 × 3
Sulfate ion
PDB codes: 4e4a(A), 4jsa(A), 4jss(A).

 

 Cluster 4 contains 4 ligand types

Selection shortcuts: select all/none invert selection.
Ligand Description


 
1. Ligand: IMD × 2
Imidazole
PDB codes: 4hf3(A),


 
2. Ligand: 1MZ × 1
1-Methylimidazole
PDB code: 4hez(A).


 
3. Ligand: GOL × 1
Glycerol
PDB code: 2x7u(A).


 
4. Ligand: RYY × 1
N-Propyl-4-Sulfamoylbenzamide
PDB code: 3ryy(A).

 

 Cluster 5 contains 3 ligand types

Selection shortcuts: select all/none invert selection.
Ligand Description


 
1. Ligand: MES × 6
2-(N-Morpholino)-Ethanesulfonic acid
PDB codes: 3m98(A), 3myq(A), 3sap(A), 3sbh(A), 4kni(A), 4knj(A).


 
2. Ligand: GOL × 2
Glycerol
PDB codes: 4ilx(A), 4itp(A).


 
3. Ligand: UNX-UNX-UNX-UNX-UNX-UNX-UNX-UNX × 1
UNX=Unknown atom or ion.
PDB code: 3hlj(A).

 

 Cluster 6 contains 3 ligand types

Selection shortcuts: select all/none invert selection.
Ligand Description

_Zn
 
1. Metal: _ZN × 1
PDB code: 4lp6(A).


 
2. Ligand: GOL × 1
Glycerol
PDB code: 2q38(A).


 
3. Ligand: RCO × 1
Resorcinol
PDB code: 4e49(A).

 

spacer

spacer