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UniProt functional annotation for P11941 | ||
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| UniProt code: P11941. |
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| Organism: | |
Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri). |
| Taxonomy: | |
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes; Salmonidae; Salmoninae; Oncorhynchus. |
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| Function: | |
Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. Has antibacterial activity against the Gram positive bacterium P.citreus. Has no antibacterial activity against the Gram negative bacteria E.coli and Y.ruckeri. Does not have hemolytic activity against trout erythrocytes. {ECO:0000255|PROSITE-ProRule:PRU00680, ECO:0000269|PubMed:15142536}. |
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| Catalytic activity: | |
Reaction=Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins.; EC=3.2.1.17; Evidence={ECO:0000269|PubMed:15142536}; |
| Biophysicochemical properties: | |
pH dependence: Optimum pH is 4.5-5.5. No activity above pH 8.8. {ECO:0000269|PubMed:15142536}; Temperature dependence: Optimum temperature is 33-49 degrees Celsius. Retains 25% of its maximal activity after heating 10 minutes at 80 degrees Celsius. {ECO:0000269|PubMed:15142536}; |
| Subcellular location: | |
Secreted. |
| Mass spectrometry: | |
Mass=14252; Method=MALDI; Evidence={ECO:0000269|PubMed:15142536}; |
| Similarity: | |
Belongs to the glycosyl hydrolase 22 family. {ECO:0000255|PROSITE-ProRule:PRU00680}. |
Annotations taken from UniProtKB at the EBI.