|
|
||
|
|
|
|
|
UniProt functional annotation for P21310 | ||
|
|
|
|
|
|
||
| UniProt code: P21310. |
|
||
| Organism: | |
Pseudomonas putida (Arthrobacter siderocapsulatus). |
| Taxonomy: | |
Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales; Pseudomonadaceae; Pseudomonas. |
|
||
| Catalytic activity: | |
Reaction=L-histidine = NH4(+) + trans-urocanate; Xref=Rhea:RHEA:21232, ChEBI:CHEBI:17771, ChEBI:CHEBI:28938, ChEBI:CHEBI:57595; EC=4.3.1.3; Evidence={ECO:0000269|PubMed:7947813, ECO:0000269|PubMed:8024588, ECO:0000269|PubMed:8204579, ECO:0000269|PubMed:8239649}; |
| Pathway: | |
Amino-acid degradation; L-histidine degradation into L- glutamate; N-formimidoyl-L-glutamate from L-histidine: step 1/3. |
| Subunit: | |
Homotetramer. |
| Subcellular location: | |
Cytoplasm {ECO:0000305}. |
| Induction: | |
By histidine and urocanate. |
| Ptm: | |
Contains an active site 4-methylidene-imidazol-5-one (MIO), which is formed autocatalytically by cyclization and dehydration of residues Ala-Ser-Gly. |
| Similarity: | |
Belongs to the PAL/histidase family. {ECO:0000305}. |
Annotations taken from UniProtKB at the EBI.