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UniProt functional annotation for P43628 | ||
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| UniProt code: P43628. |
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| Organism: | |
Homo sapiens (Human). |
| Taxonomy: | |
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. |
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| Function: | |
Receptor on natural killer (NK) cells for HLA-C alleles (HLA- Cw1, HLA-Cw3 and HLA-Cw7). Inhibits the activity of NK cells thus preventing cell lysis. |
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| Subunit: | |
Interacts with ARRB2. {ECO:0000269|PubMed:18604210}. |
| Subcellular location: | |
Cell membrane; Single-pass type I membrane protein. |
| Similarity: | |
Belongs to the immunoglobulin superfamily. {ECO:0000305}. |
Annotations taken from UniProtKB at the EBI.