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PDBsum entry 1az8

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Serine protease PDB id
1az8
Contents
Protein chain
223 a.a.
Ligands
IN4
Waters ×69

References listed in PDB file
Key reference
Title Unexpected binding mode of a bis-Phenylamidine factor xa inhibitor complexed to bovine trypsin
Authors R.Alexander, T.Maduskuie, K.Mcnamara, A.Smallwood, A.Wei, P.Stouten.
Ref. To be Published ...
Secondary reference #1
Title Crystal structures of factor xa specific inhibitors in complex with trypsin: structural grounds for inhibition of factor xa and selectivity against thrombin.
Authors M.T.Stubbs, R.Huber, W.Bode.
Ref. FEBS Lett, 1995, 375, 103-107. [DOI no: 10.1016/0014-5793(95)01190-P]
PubMed id 7498454
Full text Abstract
Secondary reference #2
Title The single calcium-Binding site of crystallin bovin beta-Trypsin.
Authors W.Bode, P.Schwager.
Ref. FEBS Lett, 1975, 56, 139-143. [DOI no: 10.1016/0014-5793(75)80128-1]
PubMed id 1157929
Full text Abstract
Secondary reference #3
Title The refined crystal structure of bovine beta-Trypsin at 1.8 a resolution. I. Crystallization, Data collection and application of patterson search technique.
Authors H.Fehlhammer, W.Bode.
Ref. J Mol Biol, 1975, 98, 683-692. [DOI no: 10.1016/S0022-2836(75)80004-0]
PubMed id 1238577
Full text Abstract
Figure 1.
Fro. 1. Section ~,8 at ~ = 120 ° through the rotationfunction otainedwith 10 ° step widths and 8 A to 2.5 A resolution data. The contours are drawn at arbitrary eqal intervals, the first broken line representing hemean valueof the function.
Figure 2.
FIO. 2. Harker sections through the translation function: (a) section ~,y, at z = 1/2, (b) sootion ~,z at y = 1/2 and (e) section y,z at x 1/2. Data from 10 A to 4 A resolution were used for the calculation. h contours aredrawn at arbitrary equal intervals, the first broke lino represent- ing the mean value of the function.
The above figures are reproduced from the cited reference with permission from Elsevier
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