PDBsum entry 1aq7

Hydrolase/hydrolase inhibitor

PDB id: 1aq7

Contents

Protein chain

223 a.a. *

Ligands

34H-DIL-XPR-AG2

Waters ×212

* Residue conservation analysis

PDB id:

1aq7

Name:

Hydrolase/hydrolase inhibitor

Title:

Trypsin with inhibitor aeruginosin 98-b

Structure:

Trypsin. Chain: a. Aeruginosin 98-b. Chain: b. Engineered: yes

Source:

Bos taurus. Cattle. Organism_taxid: 9913. Organ: pancreas. Synthetic: yes. Microcystis aeruginosa (nies-28). Organism_taxid: 267869

Resolution:

2.20Å R-factor: 0.164 R-free: 0.237

Authors:

B.Sandler,M.Murakami,J.Clardy

Key ref:

B.Sandler et al. (1998). Atomic structure of the trypsin-Aeruginosin 98-B complex. J am chem soc, 120, 595-596.

Date:

07-Aug-97 Release date: 25-Feb-98

Protein chain

P38501  (NIR_ALCFA) -  Copper-containing nitrite reductase from Alcaligenes faecalis

Seq: 376 a.a.

Struc: 223 a.a.*

* PDB and UniProt seqs differ at 175 residue positions (black crosses)

Enzyme reactions

• Enzyme class: E.C.3.4.21.4 - trypsin.
• Reaction: Preferential cleavage: Arg-|-Xaa, Lys-|-Xaa.