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UniProt functional annotation for Q07960 | ||
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| UniProt code: Q07960. |
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| Organism: | |
Homo sapiens (Human). |
| Taxonomy: | |
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. |
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| Function: | |
GTPase activator for the Rho, Rac and Cdc42 proteins, converting them to the putatively inactive GDP-bound state. Cdc42 seems to be the preferred substrate. |
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| Subunit: | |
Found in a complex with XPO7, EIF4A1, ARHGAP1, VPS26A, VPS29, VPS35 and SFN. Interacts with BNIPL. {ECO:0000269|PubMed:12901880, ECO:0000269|PubMed:15282546, ECO:0000269|PubMed:9262406}. |
| Subcellular location: | |
Cytoplasm. |
| Tissue specificity: | |
Ubiquitous. |
| Sequence caution: | |
Sequence=AAA16142.1; Type=Erroneous initiation; Evidence={ECO:0000305}; |
Annotations taken from UniProtKB at the EBI.