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UniProt functional annotation for P00327 | ||
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| UniProt code: P00327. |
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| Organism: | |
Equus caballus (Horse). |
| Taxonomy: | |
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus. |
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| Catalytic activity: | |
Reaction=a primary alcohol + NAD(+) = an aldehyde + H(+) + NADH; Xref=Rhea:RHEA:10736, ChEBI:CHEBI:15378, ChEBI:CHEBI:15734, ChEBI:CHEBI:17478, ChEBI:CHEBI:57540, ChEBI:CHEBI:57945; EC=1.1.1.1; |
| Catalytic activity: | |
Reaction=a secondary alcohol + NAD(+) = a ketone + H(+) + NADH; Xref=Rhea:RHEA:10740, ChEBI:CHEBI:15378, ChEBI:CHEBI:17087, ChEBI:CHEBI:35681, ChEBI:CHEBI:57540, ChEBI:CHEBI:57945; EC=1.1.1.1; |
| Cofactor: | |
Name=Zn(2+); Xref=ChEBI:CHEBI:29105; Evidence={ECO:0000269|PubMed:15299346}; Note=Binds 2 Zn(2+) ions per subunit. {ECO:0000269|PubMed:15299346}; |
| Subunit: | |
Dimer of identical or non-identical chains of two types (E and S) coded by 2 separate genes at different loci. |
| Subcellular location: | |
Cytoplasm. |
| Similarity: | |
Belongs to the zinc-containing alcohol dehydrogenase family. Class-I subfamily. {ECO:0000305}. |
Annotations taken from UniProtKB at the EBI.