UniProt functional annotation for P0A2K1

UniProt code: P0A2K1.

Organism: Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720).
Taxonomy: Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales; Enterobacteriaceae; Salmonella.
 
Function: The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
 
Catalytic activity: L-serine + 1-C-(indol-3-yl)glycerol 3- phosphate = L-tryptophan + D-glyceraldehyde 3-phosphate + H(2)O.
Cofactor: Pyridoxal phosphate.
Pathway: Amino-acid biosynthesis; L-tryptophan biosynthesis; L- tryptophan from chorismate: step 5/5.
Subunit: Tetramer of two alpha and two beta chains. {ECO:0000269|PubMed:9201907}.
Similarity: Belongs to the TrpB family. {ECO:0000305}.

Annotations taken from UniProtKB at the EBI.