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PDBsum entry 1wzw

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protein links
Ligase PDB id
1wzw
Jmol
Contents
Protein chain
150 a.a. *
Waters ×32
* Residue conservation analysis
PDB id:
1wzw
Name: Ligase
Title: Crystal structure of ubch8
Structure: Ubiquitin-conjugating enzyme e2 l6. Chain: a. Synonym: ubiquitin-conjugating enzyme ubch8, ubiquitin- protein ligase l6, ubiquitin carrier protein l6, ubch8, retinoic acid induced gene b protein, rig-b. Engineered: yes
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562.
Resolution:
2.40Å     R-factor:   0.203     R-free:   0.274
Authors: T.Mizushima,M.Suzuki,N.Teshima,T.Yamane,S.Murata,K.Tanaka
Key ref: T.Mizushima et al. Crystal structure of ubch8. To be published, .
Date:
10-Mar-05     Release date:   22-Mar-05    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chain
Pfam   ArchSchema ?
O14933  (UB2L6_HUMAN) -  Ubiquitin/ISG15-conjugating enzyme E2 L6
Seq:
Struc:
153 a.a.
150 a.a.
Key:    PfamA domain  Secondary structure  CATH domain

 Enzyme reactions 
   Enzyme class: E.C.6.3.2.19  - Ubiquitin--protein ligase.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]
      Reaction: ATP + ubiquitin + protein lysine = AMP + diphosphate + protein N-ubiquityllysine
ATP
+ ubiquitin
+ protein lysine
= AMP
+ diphosphate
+ protein N-ubiquityllysine
Molecule diagrams generated from .mol files obtained from the KEGG ftp site
 Gene Ontology (GO) functional annotation 
  GO annot!
  Cellular component     cytosol   1 term 
  Biological process     innate immune response   7 terms 
  Biochemical function     protein binding     6 terms