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PDBsum entry 1whm

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protein links
Antitumor protein PDB id
1whm
Jmol
Contents
Protein chain
92 a.a.
PDB id:
1whm
Name: Antitumor protein
Title: Solution structure of the 2nd cap-gly domain in human cylindromatosis tumor suppressor cyld
Structure: Cylindromatosis tumor suppressor cyld. Chain: a. Fragment: cap-gly domain. Synonym: kiaa0849 protein. Engineered: yes
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: kazusa cdna fh04363. Other_details: cell-free protein synthesis
NMR struc: 20 models
Authors: K.Saitok,S.Koshiba,M.Inoue,T.Kigawa,S.Yokoyama,Riken Structural Genomics/proteomics Initiative (Rsgi)
Key ref: K.Saitok et al. Solution structure of the 2nd cap-Gly domain in human cylindromatosis tumor suppressor cyld. To be published, .
Date:
28-May-04     Release date:   28-Nov-04    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chain
Pfam   ArchSchema ?
Q9NQC7  (CYLD_HUMAN) -  Ubiquitin carboxyl-terminal hydrolase CYLD
Seq:
Struc:
 
Seq:
Struc:
956 a.a.
92 a.a.*
Key:    PfamA domain  Secondary structure  CATH domain
* PDB and UniProt seqs differ at 14 residue positions (black crosses)

 Enzyme reactions 
   Enzyme class: E.C.3.4.19.12  - Ubiquitinyl hydrolase 1.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]
      Reaction: Thiol-dependent hydrolysis of ester, thiolester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).