spacer
spacer

PDBsum entry 1vkz

Go to PDB code: 
protein ligands Protein-protein interface(s) links
Ligase PDB id
1vkz
Jmol
Contents
Protein chains
391 a.a. *
Ligands
EDO
Waters ×121
* Residue conservation analysis
PDB id:
1vkz
Name: Ligase
Title: Crystal structure of phosphoribosylamine--glycine ligase (tm thermotoga maritima at 2.30 a resolution
Structure: Phosphoribosylamine--glycine ligase. Chain: a, b. Synonym: gars, glycinamide ribonucleotide synthetase, phosphoribosylglycinamide synthetase. Engineered: yes. Mutation: yes
Source: Thermotoga maritima. Organism_taxid: 2336. Gene: purd, tm1250. Expressed in: escherichia coli. Expression_system_taxid: 562.
Resolution:
2.30Å     R-factor:   0.216     R-free:   0.264
Authors: Joint Center For Structural Genomics (Jcsg)
Key ref: Joint center for structural genomics (jcsg) Crystal structure of phosphoribosylamine--Glycine ligase (tm1250) from thermotoga maritima at 2.30 a resolution. To be published, .
Date:
29-Jun-04     Release date:   24-Aug-04    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chains
Pfam   ArchSchema ?
Q9X0X7  (PUR2_THEMA) -  Phosphoribosylamine--glycine ligase
Seq:
Struc:
400 a.a.
391 a.a.
Key:    PfamA domain  Secondary structure  CATH domain

 Enzyme reactions 
   Enzyme class: E.C.6.3.4.13  - Phosphoribosylamine--glycine ligase.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]

      Pathway:
Purine Biosynthesis (early stages)
      Reaction: ATP + 5-phospho-D-ribosylamine + glycine = ADP + phosphate + N1- (5-phospho-D-ribosyl)glycinamide
ATP
+ 5-phospho-D-ribosylamine
+
glycine
Bound ligand (Het Group name = EDO)
matches with 50.00% similarity
= ADP
+ phosphate
+ N(1)- (5-phospho-D-ribosyl)glycinamide
Molecule diagrams generated from .mol files obtained from the KEGG ftp site
 Gene Ontology (GO) functional annotation 
  GO annot!
  Biological process     purine base biosynthetic process   3 terms 
  Biochemical function     catalytic activity     8 terms