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PDBsum entry 1ub7

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protein ligands Protein-protein interface(s) links
Transferase PDB id
1ub7
Jmol
Contents
Protein chains
321 a.a. *
Ligands
GOL ×10
Waters ×327
* Residue conservation analysis
PDB id:
1ub7
Name: Transferase
Title: The crystal analysis of beta-keroacyl-[acyl carrier protein] iii (fabh)from thermus thermophilus.
Structure: 3-oxoacyl-[acyl-carrier protein] synthase. Chain: a, b, c, d. Synonym: beta-ketoacyl-acp synthase iii. Engineered: yes. Mutation: yes
Source: Thermus thermophilus. Organism_taxid: 300852. Strain: hb8. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Biol. unit: Dimer (from PQS)
Resolution:
2.30Å     R-factor:   0.193     R-free:   0.241
Authors: E.Inagaki,M.Miyano,T.H.Tahirov,Riken Structural Genomics/pro Initiative (Rsgi)
Key ref: E.Inagaki et al. The crystal structure of beta-Ketoacyl-[Acyl carrier protein] synthase III (fabh) from thermus thermophilus. To be published, .
Date:
31-Mar-03     Release date:   15-Apr-03    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chains
Pfam   ArchSchema ?
Q7SI99  (Q7SI99_THETH) -  3-oxoacyl-[acyl-carrier-protein] synthase 3
Seq:
Struc:
322 a.a.
321 a.a.*
Key:    PfamA domain  Secondary structure  CATH domain
* PDB and UniProt seqs differ at 1 residue position (black cross)

 Enzyme reactions 
   Enzyme class: E.C.2.3.1.180  - Beta-ketoacyl-[acyl-carrier-protein] synthase Iii.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]
      Reaction: Acetyl-CoA + malonyl-[acyl-carrier-protein] = acetoacetyl-[acyl-carrier- protein] + CoA + CO2
Acetyl-CoA
+
malonyl-[acyl-carrier-protein]
Bound ligand (Het Group name = GOL)
matches with 55.56% similarity
= acetoacetyl-[acyl-carrier- protein]
+ CoA
+ CO(2)
Molecule diagrams generated from .mol files obtained from the KEGG ftp site
 Gene Ontology (GO) functional annotation 
  GO annot!
  Cellular component     cytoplasm   1 term 
  Biological process     metabolic process   5 terms 
  Biochemical function     catalytic activity     6 terms