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PDBsum entry 1pff

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protein ligands Protein-protein interface(s) links
Lyase PDB id
1pff
Jmol
Contents
Protein chains
331 a.a. *
Ligands
EDO ×21
PEG ×3
Waters ×339
* Residue conservation analysis
PDB id:
1pff
Name: Lyase
Title: Crystal structure of homocysteine alpha-, gamma-lyase at 1.8 angstroms
Structure: Methionine gamma-lyase. Chain: a, b. Ec: 4.4.1.11
Source: Trichomonas vaginalis. Organism_taxid: 5722
Biol. unit: Tetramer (from PDB file)
Resolution:
2.50Å     R-factor:   0.180     R-free:   0.208
Authors: T.W.Allen,V.Sridhar,S.G.Prasad,Q.Han,M.Xu,Y.Tan,R.M.Hoffman, S.Ramaswamy
Date:
26-May-03     Release date:   10-Aug-04    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chains
Pfam   ArchSchema ?
O15565  (O15565_TRIVA) -  Methionine gamma-lyase
Seq:
Struc:
398 a.a.
331 a.a.
Key:    PfamA domain  Secondary structure  CATH domain

 Enzyme reactions 
   Enzyme class: E.C.4.4.1.11  - Methionine gamma-lyase.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]
      Reaction: L-methionine + H2O = methanethiol + NH3 + 2-oxobutanoate
L-methionine
+ H(2)O
= methanethiol
+ NH(3)
+
2-oxobutanoate
Bound ligand (Het Group name = EDO)
matches with 57.00% similarity
      Cofactor: Pyridoxal 5'-phosphate
Pyridoxal 5'-phosphate
Molecule diagrams generated from .mol files obtained from the KEGG ftp site
 Gene Ontology (GO) functional annotation 
  GO annot!
  Biochemical function     catalytic activity     2 terms