PDBsum entry 1bru

Serine protease

PDB id: 1bru

Contents

Protein chain

241 a.a. *

Ligands

1NB

Waters ×194

* Residue conservation analysis

PDB id:

1bru

Name:

Serine protease

Title:

Structure of porcine pancreatic elastase complexed with the elastase inhibitor gr143783

Structure:

Elastase. Chain: p. Synonym: ppe. Other_details: inhibitor gr143783 covalently attached to ppe, bond between c 30 (inhibitor) and og ser 195

Source:

Sus scrofa. Pig. Organism_taxid: 9823. Organ: pancreas

Resolution:

2.30Å R-factor: 0.147

Authors:

H.Jhoti,O.M.P.Singh,A.Wonacott

Key ref:

H.Jhoti et al. To be published, .

Date:

24-Aug-98 Release date: 25-Aug-99

Protein chain

P08419  (CEL2A_PIG) -  Chymotrypsin-like elastase family member 2A from Sus scrofa

Seq: 269 a.a.

Struc: 241 a.a.

Enzyme reactions

• Enzyme class: E.C.3.4.21.71 - pancreatic elastase Ii.
• Reaction: Preferential cleavage: Leu-|-Xaa, Met-|-Xaa and Phe-|-Xaa. Hydrolyzes elastin.