Ligand clusters for UniProt code Q9Y6E0

Ligand clusters for Q9Y6E0: Serine/threonine-protein kinase 24 from Homo sapiens

		Top 6 (of 22) ligand clusters Cluster 1. 32 ligand types 38 ligands Cluster 2. 2 ligand types 2 ligands Cluster 3. 2 ligand types 2 ligands Cluster 4. 1 ligand type 1 ligand Cluster 5. 1 ligand type 1 ligand Cluster 6. 2 ligand types 7 ligands
Representative protein: 4w8eA

Structures

PDB		Schematic diagram
4w8eA
3ckxA
4qmxA
4qmnA
7b30A
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Cluster 1 contains 32 ligand types (of which only 20 are listed. Click for all)

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Ligand		Description
_Mn		1. Metal: _MN × 4 PDB codes: 3a7j(A), 4o27(B), 4u8z(A).
_Mg		2. Metal: _MG × 2 PDB codes: 4qml(A), 4qmu(A).
		3. Ligand: 1N1 × 1 dasatinib N-(2-Chloro-6-Methylphenyl)-2-({6-[4-(2-Hydroxyethyl) piperazin-1-Yl]-2-Methylpyrimidin-4- Yl}amino)-1,3- Thiazole-5-Carboxamide PDB code: 4qms(A).
		4. Ligand: ADE × 1 adenine Adenine PDB code: 3a7i(A).
		5. Ligand: B49 × 1 sunitinib N-[2-(Diethylamino)ethyl]-5-[(Z)-(5-Fluoro-2-Oxo-1,2- Dihydro-3h-Indol-3-Ylidene)methyl]-2,4- Dimethyl-1h- Pyrrole-3-Carboxamide PDB code: 4qmz(A).
		6. Ligand: DB8 × 1 bosutinib 4-[(2,4-Dichloro-5-Methoxyphenyl)amino]-6-Methoxy-7-[3- (4-Methylpiperazin-1-Yl)propoxy]quinoline- 3- Carbonitrile PDB code: 4qmn(A).
		7. Ligand: H1N × 1 hesperidin N-[2-Oxo-3-((E)-Phenyl{[4-(Piperidin-1-Ylmethyl) phenyl]imino}methyl)-2,6-Dihydro-1h-Indol-5- Yl]ethanesulfonamide PDB code: 4qmt(A).
		8. Ligand: ADP × 2 Adenosine-5'-Diphosphate PDB codes: 3a7j(A), 4o27(B).
		9. Ligand: STU × 2 Staurosporine PDB codes: 3ckx(A), 4qmy(A).
		10. Ligand: 34L × 1 (8z)-8-(1h-Imidazol-5-Ylmethylidene)-6,8-Dihydro-7h-[1, 3]thiazolo[5,4-E]indol-7-One PDB code: 4qmo(A).
		11. Ligand: 34U × 1 1-{2-[5-(2-Methoxyethoxy)-1h-Benzimidazol-1- Yl]quinolin-8-Yl}piperidin-4-Amine PDB code: 4qmq(A).
		12. Ligand: 34W × 1 N-{2-[(1s,4r)-6-{[4-(Cyclobutylamino)-5- (Trifluoromethyl)pyrimidin-2-Yl]amino}-1,2,3,4- Tetrahydro-1,4-Epiminonaphthalen-9-Yl]-2- Oxoethyl}acetamide PDB code: 4qmv(A).
		13. Ligand: 35R × 1 1-Cyclopropyl-3-{3-[5-(Morpholin-4-Ylmethyl)-1h- Benzimidazol-2-Yl]-1h-Pyrazol-4-Yl}urea PDB code: 4qmm(A).
		14. Ligand: 3FE × 1 3-[4-(Morpholin-4-Yl)-7h-Pyrrolo[2,3-D]pyrimidin-5- Yl]benzonitrile PDB code: 4u8z(A).
		15. Ligand: 3JA × 1 5-(1-Methyl-1h-Pyrazol-4-Yl)-4-(Morpholin-4-Yl)-7h- Pyrrolo[2,3-D]pyrimidine PDB code: 4w8d(A).
		16. Ligand: 3JB × 1 3-{4-[(2r)-2-(5-Methyl-1,2,4-Oxadiazol-3-Yl)morpholin- 4-Yl]-7h-Pyrrolo[2,3-D]pyrimidin-5- Yl}benzonitrile PDB code: 4w8e(A).
		17. Ligand: 59T × 1 8-[(Trans-5-Amino-1,3-Dioxan-2-Yl)methyl]-6-[2-Chloro- 4-(6-Methylpyridin-2-Yl)phenyl]-2- (Methylamino) pyrido[2,3-D]pyrimidin-7(8h)-One PDB code: 7b30(A).
		18. Ligand: 627 × 1 N-[(3e)-5-[(2r)-2-Methoxy-2-Phenylacetyl]pyrrolo[3,4- C]pyrazol-3(5h)-Ylidene]-4-(4- Methylpiperazin-1-Yl) benzamide PDB code: 4qo9(A).
		19. Ligand: ACT × 1 Acetate ion PDB code: 4qmm(A).
		20. Ligand: ANP × 1 Phosphoaminophosphonic acid-Adenylate ester PDB code: 4qml(A).
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Cluster 2 contains 2 ligand types

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Ligand		Description
		1. Ligand: EDO × 1 1,2-Ethanediol PDB code: 4qo9(A).
		2. Ligand: PG4 × 1 Tetraethylene glycol PDB code: 4qmo(A).

Cluster 3 contains 2 ligand types

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Ligand		Description
		1. Ligand: EDO × 1 1,2-Ethanediol PDB code: 7b33(A).
		2. Ligand: PEG × 1 Di(hydroxyethyl)ether PDB code: 4qmq(A).

Cluster 4 contains 1 ligand type

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Ligand		Description
		1. Ligand: PGE × 1 Triethylene glycol PDB code: 4qo9(A).

Cluster 5 contains 1 ligand type

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Ligand		Description
		1. Ligand: PGE × 1 Triethylene glycol PDB code: 4qo9(A).

Cluster 6 contains 2 ligand types

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Ligand		Description
_Cl		1. Metal: _CL × 4 PDB codes: 4qmo(A), 4qms(A), 4qmy(A), 4qmz(A).
		2. Ligand: EDO × 3 Ethane-1,2-Diol PDB codes: 4qml(A), 7b33(A), 7b34(A).