Ligand clusters for UniProt code P49841

Ligand clusters for P49841: Glycogen synthase kinase-3 beta from Homo sapiens

		Top 6 (of 24) ligand clusters Cluster 1. 74 ligand types 86 ligands Cluster 2. 12 ligand types 36 ligands Cluster 3. 2 ligand types 2 ligands Cluster 4. 4 ligand types 6 ligands Cluster 5. 1 ligand type 1 ligand Cluster 6. 2 ligand types 2 ligands
Representative protein: 4nm5A

Structures

PDB		Schematic diagram
4nm5A
3sd0A
3f88A
3f7zA
4acdA
		more ...

Cluster 1 contains 74 ligand types (of which only 20 are listed. Click for all)

Use checkboxes to select ligands to display in RasMol, Jmol, or download as an SDF file. Selection shortcuts: select all/none invert selection.
Ligand		Description
		1. Ligand: DMS × 3 dimethyl sulfoxide Dimethyl sulfoxide PDB codes: 6hk4(A), 6hk7(A).
		2. Ligand: GOL × 2 glycerin Glycerol PDB codes: 6hk3(A), 6hk4(A).
		3. Ligand: ADP × 5 Adenosine-5'-Diphosphate PDB codes: 1j1c(A), 4nm0(A), 4nm3(A), 4nm5(A), 4nm7(A).
		4. Ligand: 3NG × 3 5-[(3-Chlorophenyl)amino]benzo[c][2,6]naphthyridine-8- Carboxylic acid PDB codes: 7z1f(A), 7z1g(A).
		5. Ligand: 65C × 2 Chir99021 PDB codes: 5hln(A), 6b8j(A).
		6. Ligand: 6VL × 2 (4~{s})-4-Ethyl-7,7-Dimethyl-4-Phenyl-2,6,8,9- Tetrahydropyrazolo[3,4-B]quinolin-5-One PDB codes: 5kpl(A), 5t31(A).
		7. Ligand: ANP × 2 Phosphoaminophosphonic acid-Adenylate ester PDB codes: 1j1b(A), 1pyx(A).
		8. Ligand: 0KD × 1 N-(Pyridin-3-Yl)-2-(Thiophen-3-Yl)-3h-Imidazo[4,5- B]pyridine-7-Carboxamide PDB code: 4dit(A).
		9. Ligand: 1JX × 1 (2r)-2-Methyl-1,4-Dihydropyrido[2,3-B]pyrazin-3(2h)-One PDB code: 4j71(A).
		10. Ligand: 2HT × 1 3-Methylbenzonitrile PDB code: 3f88(A).
		11. Ligand: 2WE × 1 2-[2-(Cyclopropylcarbonylamino)pyridin-4-Yl]-4-Methoxy- 1,3-Thiazole-5-Carboxamide PDB code: 4ptc(A).
		12. Ligand: 2WF × 1 N-[4-(Isoquinolin-7-Yl)pyridin-2- Yl]cyclopropanecarboxamide PDB code: 4pte(A).
		13. Ligand: 2WG × 1 2-{2-[(Cyclopropylcarbonyl)amino]pyridin-4-Yl}-4- Methoxypyrimidine-5-Carboxamide PDB code: 4ptg(A).
		14. Ligand: 34O × 1 2-(1,3-Benzodioxol-5-Yl)-5-[(3-Fluoro-4-Methoxybenzyl) sulfanyl]-1,3,4-Oxadiazole PDB code: 3f7z(A).
		15. Ligand: 39I × 1 ~{N}4-(3-Cyclopropyl-1~{h}-Pyrazol-5-Yl)-~{N}2- (Phenylmethyl)thieno[3,2-D]pyrimidine-2,4-Diamine PDB code: 7oy5(A).
		16. Ligand: 3HT × 1 5-[1-(4-Methoxyphenyl)-1h-Benzimidazol-6-Yl]-1,3,4- Oxadiazole-2(3h)-Thione PDB code: 3f88(A).
		17. Ligand: 3UO × 1 2-[(Cyclopropylcarbonyl)amino]-N-(4-Methoxypyridin-3- Yl)pyridine-4-Carboxamide PDB code: 5f94(A).
		18. Ligand: 3UP × 1 2-[(Cyclopropylcarbonyl)amino]-N-(4-Phenylpyridin-3- Yl)pyridine-4-Carboxamide PDB code: 5f95(A).
		19. Ligand: 553 × 1 (7s)-2-(2-Aminopyrimidin-4-Yl)-7-(2-Fluoroethyl)-1,5,6, 7-Tetrahydro-4h-Pyrrolo[3,2-C]pyridin-4-One PDB code: 3du8(A).
		20. Ligand: 55E × 1 4-(4-Hydroxy-3-Methylphenyl)-6-Phenylpyrimidin-2(5h)- One PDB code: 3q3b(A).
+ more. Press for full list

Cluster 2 contains 12 ligand types

Selection shortcuts: select all/none invert selection.
Ligand		Description
		1. Ligand: GOL × 1 glycerin Glycerol PDB code: 4nm0(A).
		2. Ligand: SO4 × 14 Sulfate ion PDB codes: 1gng(A), 3zrk(A), 3zrl(A), 3zrm(A), 4afj(A), 4j71(A), 5k5n(A), 5oy4(A), 7b6f(A).
		3. Ligand: MLI × 5 Malonate ion PDB codes: 6h0u(A), 6hk3(A), 6hk4(A), 7z1g(A),
		4. Ligand: PO4 × 5 Phosphate ion PDB codes: 1i09(A), 1uv5(A), 3zdi(A), 4j1r(A), 6v6l(A).
		5. Ligand: ACT × 3 Acetate ion PDB codes: 6tcu(A), 6y9r(A), 6y9s(A).
		6. Ligand: EPE × 2 4-(2-Hydroxyethyl)-1-Piperazine ethanesulfonic acid PDB codes: 1h8f(A), 3sd0(A).
		7. Ligand: FLC × 1 Citrate anion PDB code: 1r0e(A).
		8. Ligand: MES × 1 2-(N-Morpholino)-Ethanesulfonic acid PDB code: 5hln(A).
		9. Ligand: MLA × 1 Malonic acid PDB code: 3say(A).
		10. Ligand: PRO-PRO-PRO-SEP-PRO-CYS × 1 SEP=Phosphoserine. PDB code: 4nm7(A).
		11. Ligand: PRO-PRO-PRO-TPO-PRO-ARG × 1 TPO=Phosphothreonine. PDB code: 4nm5(A).
		12. Ligand: VAL-SEP-ARG-ARG × 1 SEP=Phosphoserine. PDB code: 6b8j(A).

Cluster 3 contains 2 ligand types

Selection shortcuts: select all/none invert selection.
Ligand		Description
		1. Ligand: GLY-SER-HIS-GLY-HIS-HIS-HIS-HIS × 1 PDB code: 6hk3(A).
		2. Ligand: GLY-SER-HIS-GLY-HIS-HIS-HIS-HIS-HIS × 1 PDB code: 6hk4(A).

Cluster 4 contains 4 ligand types

Selection shortcuts: select all/none invert selection.
Ligand		Description
		1. Ligand: GOL × 2 glycerin Glycerol PDB codes: 6h0u(A),
		2. Ligand: EPE × 2 4-(2-Hydroxyethyl)-1-Piperazine ethanesulfonic acid PDB codes: 1h8f(A), 3sd0(A).
		3. Ligand: FLC × 1 Citrate anion PDB code: 1r0e(A).
		4. Ligand: MES × 1 2-(N-Morpholino)-Ethanesulfonic acid PDB code: 5hln(A).

Cluster 5 contains 1 ligand type

Selection shortcuts: select all/none invert selection.
Ligand		Description
		1. Ligand: ALA-GLY-GLY-ALA-ALA-ALA-ALA-ALA × 1 PDB code: 2jld(A).

Cluster 6 contains 2 ligand types

Selection shortcuts: select all/none invert selection.
Ligand		Description
		1. Ligand: DMS × 1 dimethyl sulfoxide Dimethyl sulfoxide PDB code: 6hk4(A).
		2. Ligand: OHK × 1 ~{N}-(Oxan-4-Ylmethyl)-6-(5-Propan-2-Yloxypyridin-3- Yl)imidazo[1,5-A]pyridine-3-Carboxamide PDB code: 6y9s(A).