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Ligand clusters for UniProt code P40337

Ligand clusters for P40337: von Hippel-Lindau disease tumor suppressor from Homo sapiens

6 ligand clusters


Cluster 1. 41 ligand types 50 ligands		Cluster 2. 1 ligand type 1 ligand		Cluster 3. 3 ligand types 12 ligands		Cluster 4. 1 ligand type 2 ligands		Cluster 5. 1 ligand type 1 ligand		Cluster 6. 1 ligand type 1 ligand

Representative protein: 6hayB

Structures

PDB		Schematic diagram

6hayB
4ajyV
4b9kI
5t35D
6haxB
		more ...

Cluster 1 contains 41 ligand types (of which only 20 are listed. Click for all)

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Ligand

Description

1. Ligand: IPA × 2

isopropyl alcohol

Isopropyl alcohol

PDB codes: 6gmq(I), 6gmx(C).

2. Ligand: DMS × 1

dimethyl sulfoxide

Dimethyl sulfoxide

PDB code: 6hr2(B).

3. Ligand: EDO × 3

1,2-Ethanediol

PDB codes: 6hax(B), 6hay(B).

4. Ligand: 3JU × 2

(4r)-1-(3,3-Dimethylbutanoyl)-4-Hydroxy-N-[4-(4-Methyl- 1,3-Thiazol-5-Yl)benzyl]-L-Prolinamide

PDB codes: 4w9f(C),

5. Ligand: FWZ × 2

(2~{s},4~{r})-~{N}-[[2-[2-[4-[[4-[3-Azanyl-6-(2- Hydroxyphenyl)pyridazin-4-Yl]piperazin-1-
Yl]methyl]phenyl]ethoxy]-4-(4-Methyl-1,3-Thiazol-5- Yl)phenyl]methyl]-1-[(2~{s})-2-[(1-
Fluoranylcyclopropyl)carbonylamino]-3,3-Dimethyl- Butanoyl]-4-Oxidanyl-Pyrrolidine-2-Carboxamide

PDB codes: 6hax(B), 6hr2(B).

6. Ligand: TG0 × 2

(2s,4r)-1-(3-Amino-2-Methylbenzoyl)-4- Hydroxy-N-(4-(4-Methylthiazol-5-Yl)benzyl) pyrrolidine-2-
Carboxamide

PDB codes: 4b9k(C),

7. Ligand: UCK × 2

(2s,4r)-1-(2-Chlorophenyl)carbonyl-N-[(4-Chlorophenyl) methyl]-4-Oxidanyl-Pyrrolidine-2-Carboxamide

PDB codes: 4b95(C),

8. Ligand: V6F × 2

(4r)-1-Acetyl-4-Hydroxy-N-Methyl-L-Prolinamide

PDB codes: 4awj(C),

9. Ligand: ZUN × 2

(4r)-N-[4-(Dihydroxyamino)benzyl]-4-Hydroxy-1-[(3- Methylisoxazol-5-Yl)acetyl]-L-Prolinamide

PDB codes: 3zun(C),

10. Ligand: 3JF × 1

N-Acetyl-3-Methyl-L-Valyl-(4r)-4-Hydroxy-N-[4-(4- Methyl-1,3-Thiazol-5-Yl)benzyl]-L-Prolinamide

PDB code: 4w9h(C).

11. Ligand: 3JG × 1

(4r)-1-(3,3-Dimethylbutanoyl)-4-Hydroxy-N-[4-(1,3- Oxazol-5-Yl)benzyl]-L-Prolinamide

PDB code: 4w9c(C).

12. Ligand: 3JH × 1

N-Acetyl-L-Leucyl-3-Methyl-L-Valyl-(4r)-4-Hydroxy-N-[4- (4-Methyl-1,3-Thiazol-5-Yl)benzyl]-L-
Prolinamide

PDB code: 4w9j(C).

13. Ligand: 3JJ × 1

N-Acetyl-3-Methyl-L-Valyl-3-Methyl-L-Valyl-(4r)-4- Hydroxy-N-[4-(4-Methyl-1,3-Thiazol-5-Yl)benzyl]-
L- Prolinamide

PDB code: 4w9l(C).

14. Ligand: 3JK × 1

(4r)-1-(3,3-Dimethylbutanoyl)-4-Hydroxy-N-[4-(4-Methyl- 1,3-Oxazol-5-Yl)benzyl]-L-Prolinamide

PDB code: 4w9d(C).

15. Ligand: 3JO × 1

N-Acetyl-L-Phenylalanyl-3-Methyl-L-Valyl-(4r)-4- Hydroxy-N-[4-(4-Methyl-1,3-Thiazol-5-Yl)benzyl]-L-
Prolinamide

PDB code: 4w9k(C).

16. Ligand: 3JS × 1

(4r)-1-Acetyl-4-Hydroxy-L-Prolyl-(4r)-4-Hydroxy-N-[4- (4-Methyl-1,3-Thiazol-5-Yl)benzyl]-L-
Prolinamide

PDB code: 4w9i(C).

17. Ligand: 3JT × 1

(4r)-1-(3,3-Dimethylbutanoyl)-4-Hydroxy-N-[4-(1,3- Thiazol-5-Yl)benzyl]-L-Prolinamide

PDB code: 4w9e(C).

18. Ligand: 3JV × 1

(4r)-1-(3,3-Dimethylbutanoyl)-4-Hydroxy-N-[3-Methyl-4- (1,3-Thiazol-5-Yl)benzyl]-L-Prolinamide

PDB code: 4w9g(C).

19. Ligand: 4YY × 1

N-[(1-Fluorocyclopropyl)carbonyl]-3-Methyl-L-Valyl- (4r)-4-Hydroxy-N-[4-(4-Methyl-1,3-Thiazol-5-
Yl) benzyl]-L-Prolinamide

PDB code: 5nvx(C).

20. Ligand: 6Z3 × 1

(2~{s},4~{r})-1-[(2~{s})-2-[(1-Cyanocyclopropyl) carbonylamino]-3,3-Dimethyl-Butanoyl]-~{N}-[[4-(4-
Methyl-1,3-Thiazol-5-Yl)phenyl]methyl]-4-Oxidanyl- Pyrrolidine-2-Carboxamide

PDB code: 5lli(C).

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