Ligand clusters for UniProt code P28072

Ligand clusters for P28072: Proteasome subunit beta type-6 from Homo sapiens

		6 ligand clusters Cluster 1. 10 ligand types 21 ligands Cluster 2. 1 ligand type 10 ligands Cluster 3. 1 ligand type 10 ligands Cluster 4. 1 ligand type 12 ligands Cluster 5. 1 ligand type 8 ligands Cluster 6. 1 ligand type 10 ligands
Representative protein: 5le5N

Structures

PDB		Schematic diagram
5le5N
5lexN
5leyN
5lf6N
5lf3N
		more ...

Cluster 1 contains 10 ligand types

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Ligand		Description
		1. Ligand: 6V8 × 1 ixazomib [(1~{r})-1-[2-[[2,5-Bis(chloranyl) phenyl]carbonylamino]ethanoylamino]-3-Methyl- Butyl]boronic acid PDB code: 5lf7(N).
		2. Ligand: BO2 × 1 bortezomib N-[(1r)-1-(Dihydroxyboryl)-3-Methylbutyl]-N-(Pyrazin-2- Ylcarbonyl)-L-Phenylalaninamide PDB code: 5lf3(N).
__K		3. Metal: __K × 1 PDB code: 5lf4(N).
_Cl		4. Metal: _CL × 12 PDB codes: 5le5(N), 5ley(N), 5lf0(N), 5lf1(N), 5lf3(N), 5lf6(N), 5lf7(N).
		5. Ligand: 6V7 × 1 [(1~{r})-3-Methyl-1-[[(2~{s},3~{s})-3-Oxidanyl-2-[(6- Phenylpyridin-2- Yl) carbonylamino]butanoyl]amino]butyl]boronic acid PDB code: 5lf4(N).
		6. Ligand: 6V9-OAS-OAS-6VA × 1 6V9=2-Methyl-1,3-Thiazole-5-Carboxylic acid, OAS=O-Acetylserine, 6VA=(3~{r},4~{s})-4-Azanyl-2-Methyl-5-Phenyl-Pentane-2,3- Diol. PDB code: 5lez(N).
		7. Ligand: 6VC × 1 ~{N}-[(2~{s})-1-[[(2~{s},3~{r},4~{s})-2,6-Dimethyl-1,2, 3-Tris(oxidanyl)heptan-4-Yl]amino]-3- Oxidanyl-1- Oxidanylidene-Propan-2-Yl]-6-Methyl-Heptanamide PDB code: 5lf1(N).
		8. Ligand: ACE-IML-ILE-THR-6VO × 1 ACE=Acetyl group, IML=N-Methyl-Isoleucine, 6VO=(3~{r},4~{s})-4-Azanyl-2,6-Dimethyl-Heptane-2,3-Diol. PDB code: 5lf0(N).
		9. Ligand: ACT × 1 Acetate ion PDB code: 5lez(N).
		10. Ligand: KNM × 1 Ada-(Ahx)3-(Leu)3-Vinyl sulfone PDB code: 5a0q(H).

Cluster 2 contains 1 ligand type

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Ligand		Description
		1. Ligand: 1PE × 10 Pentaethylene glycol PDB codes: 5le5(N), 5lex(N), 5ley(N), 5lez(N), 5lf0(N), 5lf1(N), 5lf3(N), 5lf4(N), 5lf6(N), 5lf7(N).

Cluster 3 contains 1 ligand type

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Ligand		Description
		1. Ligand: 1PE × 10 Pentaethylene glycol PDB codes: 5le5(N), 5lex(N), 5ley(N), 5lez(N), 5lf0(N), 5lf1(N), 5lf3(N), 5lf4(N), 5lf6(N), 5lf7(N).

Cluster 4 contains 1 ligand type

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Ligand		Description
_Cl		1. Metal: _CL × 12 PDB codes: 5le5(N), 5ley(N), 5lf0(N), 5lf1(N), 5lf3(N), 5lf4(N), 5lf6(N), 5lf7(N).

Cluster 5 contains 1 ligand type

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Ligand		Description
_Cl		1. Metal: _CL × 8 PDB codes: 5le5(N), 5ley(N), 5lf0(N), 5lf1(N), 5lf3(N), 5lf4(N), 5lf6(N), 5lf7(N).

Cluster 6 contains 1 ligand type

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Ligand		Description
__K		1. Metal: __K × 10 PDB codes: 5le5(N), 5lex(N), 5ley(N), 5lez(N), 5lf0(N), 5lf1(N), 5lf3(N), 5lf4(N), 5lf6(N), 5lf7(N).