Ligand clusters for UniProt code P25098

Ligand clusters for P25098: Beta-adrenergic receptor kinase 1 from Homo sapiens

		Top 6 (of 7) ligand clusters Cluster 1. 16 ligand types 17 ligands Cluster 2. 1 ligand type 1 ligand Cluster 3. 1 ligand type 1 ligand Cluster 4. 1 ligand type 2 ligands Cluster 5. 1 ligand type 1 ligand Cluster 6. 1 ligand type 1 ligand
Representative protein: 4mk0A

Structures

PDB		Schematic diagram
4mk0A
5ukkA
3krxA
3krwA
3cikA
		more ...

Cluster 1 contains 16 ligand types

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Ligand		Description
		1. Ligand: 8PR × 1 paroxetine Paroxetine PDB code: 3v5w(A).
		2. Ligand: BA1 × 2 Balanol PDB codes: 3krw(A), 3krx(A).
		3. Ligand: 29X × 1 5-{[(3s,4r)-4-(4-Fluorophenyl)piperidin-3-Yl]methoxy}- 1h-Isoindol-1-One PDB code: 4mk0(A).
		4. Ligand: 8DJ × 1 5-[(3s,4r)-3-{[(2h-1,3-Benzodioxol-5-Yl) oxy]methyl}piperidin-4-Yl]-2-Fluoro-N-[(Pyridin-2- Yl) methyl]benzamide PDB code: 5ukk(A).
		5. Ligand: 8PV × 1 N-Benzyl-3-({[5-(Pyridin-4-Yl)-4h-1,2,4-Triazol-3- Yl]methyl}amino)benzamide PDB code: 5uvc(A).
		6. Ligand: AFM × 1 2-Fluoro-5-[(3s,4r)-3-{[(1h-Indazol-5-Yl) oxy]methyl}piperidin-4-Yl]-N-[(1h-Pyrazol-3- Yl) methyl]benzamide PDB code: 5wg3(A).
		7. Ligand: AFV × 1 2-Fluoro-5-[(3s,4r)-3-{[(1h-Indazol-5-Yl) oxy]methyl}piperidin-4-Yl]-N-[(Pyridin-2- Yl) methyl]benzamide PDB code: 5wg4(A).
		8. Ligand: EJS × 1 (4r,5r,6s)-4-[4-Fluoro-3-({[3-(Methoxymethyl)-1,2,4- Oxadiazol-5-Yl]methyl}carbamoyl)phenyl]-N-(2h- Indazol- 5-Yl)-6-Methyl-2-Oxohexahydropyrimidine-5-Carboxamide PDB code: 6c2y(A).
		9. Ligand: KZQ × 1 (4s)-4-(4-Fluorophenyl)-N-(2h-Indazol-5-Yl)-6-Methyl-2- Oxo-1,2,3,4-Tetrahydropyrimidine-5- Carboxamide PDB code: 4pnk(A).
		10. Ligand: Q1Y × 1 5-[(3s,4r)-3-{[(2h-1,3-Benzodioxol-5-Yl) oxy]methyl}piperidin-4-Yl]-2-Fluoro-N-[(2h-Indazol-3- Yl)methyl]benzamide PDB code: 6u7c(A).
		11. Ligand: QRW × 1 3-({[4-Methyl-5-(Pyridin-4-Yl)-4h-1,2,4-Triazol-3- Yl]methyl}amino)-N-[2- (Trifluoromethyl) benzyl]benzamide PDB code: 5uuu(A).
		12. Ligand: SIX × 1 2-{5-[(3s,4r)-3-{[(2h-1,3-Benzodioxol-5-Yl) oxy]methyl}piperidin-4-Yl]-2-Fluorophenyl}-N-[2-(1h- Pyrazol-4-Yl)ethyl]acetamide PDB code: 5ukl(A).
		13. Ligand: W4D × 1 3-Benzyl-6-(1h-Pyrazol-4-Yl)quinazolin-4(3h)-One PDB code: 7k7l(A).
		14. Ligand: W4G × 1 3-Benzyl-7-(1h-Pyrazol-4-Yl)quinazolin-4(3h)-One PDB code: 7k7z(A).
		15. Ligand: ZS2 × 1 (4~{s})-4-[4-Fluoranyl-3-(Isoquinolin-1- Ylmethylcarbamoyl)phenyl]-~{N}-(1~{h}-Indazol-5-Yl)-6- Methyl-2-Oxidanylidene-3,4-Dihydro-1~{h}-Pyrimidine-5- Carboxamide PDB code: 5he1(A).
		16. Ligand: ZSO × 1 5-{[(3s,4r)-4-(4-Fluorophenyl)piperidin-3-Yl]methoxy}- 2h-Indazole PDB code: 5wg5(A).

Cluster 2 contains 1 ligand type

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Ligand		Description
		1. Ligand: MES × 1 2-(N-Morpholino)-Ethanesulfonic acid PDB code: 5uuu(A).

Cluster 3 contains 1 ligand type

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Ligand		Description
		1. Ligand: GOL × 1 glycerin Glycerol PDB code: 4mk0(A).

Cluster 4 contains 1 ligand type

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Ligand		Description
		1. Ligand: SO4 × 2 Sulfate ion PDB codes: 5uuu(A), 5uvc(A).

Cluster 5 contains 1 ligand type

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Ligand		Description
		1. Ligand: SO4 × 1 Sulfate ion PDB code: 5uuu(A).

Cluster 6 contains 1 ligand type

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Ligand		Description
		1. Ligand: SO4 × 1 Sulfate ion PDB code: 5uvc(A).