Ligand clusters for UniProt code P01116

Ligand clusters for P01116: GTPase KRas from Homo sapiens

		Top 6 (of 17) ligand clusters Cluster 1. 98 ligand types 576 ligands Cluster 2. 2 ligand types 4 ligands Cluster 3. 2 ligand types 2 ligands Cluster 4. 1 ligand type 3 ligands Cluster 5. 2 ligand types 4 ligands Cluster 6. 3 ligand types 10 ligands
Representative protein: 5tarA

Structures

PDB		Schematic diagram
5tarA
6fa1B
6fa4B
5ocoB
6f76B
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Cluster 1 contains 98 ligand types (of which only 20 are listed. Click for all)

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Ligand		Description
_Mg		1. Metal: _MG × 120 PDB codes: 3gft(D), 4dsn(A), 4dso(A), 4dst(A), 4dsu(A), 4epr(A), 4ept(A), 4epv(A), 4epw(A), 4epx(A), 4epy(A), 4l8g(A), 4ldj(A), 4lrw(A), 4lyj(A), 4m1w(A), 4m22(A), 4nmm(A), 4obe(A), 4pzy(A), 4pzz(A), 4q01(A), 4q02(A), 4q03(A), 4ql3(A), 4tq9(A), 4tqa(A), 4wa7(A), 5f2e(A), 5mla(A), 5mlb(A), 5o2s(A), 5o2t(A), 5ocg(A), 5oco(B), 5oct(A), 5ufe(A), 5ufq(A), 5uk9(A), 5uqw(A), 5us4(A), 5usj(A), 5v6s(A), 5v71(A), 5v9l(A), 5v9o(A), 5vbm(A), 5vp7(A), 5vpi(A), 5vpy(A), 5vpz(A), 5vq0(A), 5vq1(A), 5vq2(A), 5vq6(A), 5vq8(A), 5w22(A), 5wha(G), 5whb(A), 5wlb(A), 5wpm(A), 5yxz(A), 5yy1(A), 6ark(A), 6asa(A), 6ase(A), 6cc9(B), 6cch(B), 6ccx(B), 6e6f(A), 6f76(B), 6fa1(B), 6fa2(D), 6fa3(B), 6fa4(B), 6gj5(A), 6gj6(A), 6gj7(A), 6gj8(A), 6god(A), 6goe(A), 6gof(A), 6gog(A), 6gom(C), 6gqt(C), 6gqw(D), 6gqx(A), 6gqy(A), 6mbt(A), 6mbu(A), 6n2j(A), 6n2k(A), 6ob2(A), 6ob3(A), 6oim(A), 6p0z(A), 6p8y(A), 6quu(A), 6quv(A), 6quw(A), 6qux(A), 6v5l(A).
		2. Ligand: GOL × 23 glycerin Glycerol PDB codes: 4dso(A), 4dst(A), 5f2e(A), 5ocg(A), 5uk9(A), 5v9u(A), 6ark(A), 6b0y(A), 6epm(R), 6epn(R), 6epo(R), 6epp(R), 6god(A), 6mbu(B), 6ob2(A), 6xgu(A), 6xha(A).
		3. Ligand: CIT × 3 citric acid Citric acid PDB codes: 6gog(A), 6gom(A), 6gqt(A).
_Zn		4. Metal: _ZN × 3 PDB codes: 1d8d(P), 6xgu(A), 6xgv(A).
		5. Ligand: DMS × 1 dimethyl sulfoxide Dimethyl sulfoxide PDB code: 4dst(A).
		6. Ligand: GDP × 115 Guanosine-5'-Diphosphate PDB codes: 4dsu(A), 4epr(A), 4ept(A), 4epv(A), 4epw(A), 4epx(A), 4epy(A), 4l8g(A), 4ldj(A), 4lpk(A), 4lrw(A), 4luc(A), 4lv6(A), 4lyf(A), 4lyh(A), 4lyj(A), 4m1o(A), 4m1s(A), 4m1t(A), 4m1w(A), 4m1y(A), 4m21(A), 4m22(A), 4obe(A), 4pzy(A), 4pzz(A), 4q01(A), 4q02(A), 4q03(A), 4ql3(A), 4tq9(A), 4tqa(A), 4wa7(A), 5f2e(A), 5mlb(A), 5o2s(A), 5tar(A), 5tb5(A), 5uk9(A), 5uqw(A), 5us4(A), 5v6s(A), 5v6v(A), 5v71(A), 5v9l(A), 5v9o(A), 5v9u(A), 5vbm(A), 5vp7(A), 5vq0(A), 5vq1(A), 5vq8(A), 5w22(A), 5wha(A), 5whb(A), 5whd(A), 5xco(A), 5yxz(A), 5yy1(A), 6ark(A), 6asa(A), 6ase(A), 6b0v(A), 6b0y(A), 6bof(A), 6e6g(A), 6h46(A), 6m9w(A), 6mbt(A), 6mbu(A), 6mqg(A), 6mqn(A), 6ms9(C), 6n2j(A), 6n2k(A), 6oim(A), 6p0z(A), 6p8w(A), 6p8x(A), 6p8y(A), 6p8z(A), 6pgo(A), 6pgp(A), 6pq3(A), 6t5b(A), 6t5v(A), 6tam(A), 6tan(A), 6usx(A), 6usz(A), 6ut0(A), 6v5l(A), 6w4f(B), 6yr8(A), 6yxw(A), 6zl5(A), 7acq(A), 7c40(A), 7c41(A).
		7. Ligand: PCW × 64 1,2-Dioleoyl-Sn-Glycero-3-Phosphocholine PDB codes: 6cc9(B), 6cch(B), 6ccx(B), 6pts(B), 6ptw(B), 6w4e(B), 6w4f(B),
		8. Ligand: GNP × 56 Phosphoaminophosphonic acid-Guanylate ester PDB codes: 3gft(A), 5ocg(A), 5oco(B), 5oct(A), 5ufe(A), 5ufq(A), 5usj(A), 5whe(A), 5wlb(A), 5wpm(A), 6cc9(B), 6cch(B), 6ccx(B), 6cu6(A), 6e6f(A), 6f76(B), 6fa1(B), 6fa2(A), 6fa3(B), 6fa4(B), 6god(A), 6goe(A), 6gof(A), 6gog(A), 6gom(A), 6gqt(A), 6gqw(A), 6gqx(A), 6gqy(A), 6mbq(A), 6mta(A), 6o36(A), 6o46(A), 6ob2(A), 6ob3(A), 6pts(B), 6ptw(B), 6v65(C), 6v6f(C), 6vc8(A), 6vjj(A), 6wgn(A), 6xgu(A), 6xgv(A), 6xha(A), 6xhb(A).
		9. Ligand: 17F × 20 O-[(S)-({(2r)-2,3-Bis[(9z)-Octadec-9- Enoyloxy]propyl}oxy)(hydroxy)phosphoryl]-L-Serine PDB codes: 6cc9(B), 6cch(B), 6ccx(B), 6pts(B), 6w4e(B), 6w4f(B).
_Ca		10. Metal: _CA × 16 PDB codes: 4lpk(A), 4luc(A), 4lv6(A), 5ufe(A), 5ufq(A), 5v6v(A), 5v9u(A), 6b0v(A), 6b0y(A), 6e6g(A), 6p8w(A), 6p8x(A), 6p8z(A).
		11. Ligand: GCP × 15 Phosphomethylphosphonic acid guanylate ester PDB codes: 4dsn(A), 4dst(A), 6bp1(A), 6gj5(A), 6gj6(A), 6gj7(A), 6gj8(A), 6quu(A), 6quv(A), 6quw(A), 6qux(A), 6zli(A), 7aca(A), 7acf(A), 7ach(A).
		12. Ligand: EDO × 9 1,2-Ethanediol PDB codes: 4dsn(A), 4dst(A), 5xco(A), 5yxz(A), 5yy1(A), 6mbq(A), 6qux(A), 6vjj(A).
		13. Ligand: SO4 × 8 Sulfate ion PDB codes: 4lyh(A), 5mla(A), 5o2t(A), 6h47(A), 6pq3(A), 6zl5(A).
		14. Ligand: GSP × 6 5'-Guanosine-Diphosphate-Monothiophosphate PDB codes: 4dso(A), 5mla(A), 5o2t(A), 5vpz(A), 5vq6(A), 6w4e(B).
		15. Ligand: PEG × 4 Di(hydroxyethyl)ether PDB codes: 5ocg(A), 5oco(B), 5oct(A), 6p0z(A).
		16. Ligand: R6W × 4 (3~{s})-5-Oxidanyl-3-[2-[[6-[[3-[(1~{s})-6-Oxidanyl-3- Oxidanylidene-1,2-Dihydroisoindol-1-Yl]- 1~{h}-Indol-2- Yl]methylamino]hexylamino]methyl]-1~{h}-Indol-3-Yl]-2, 3-Dihydroisoindol-1-One PDB codes: 7aca(A), 7acf(A), 7ach(A), 7acq(A).
		17. Ligand: D2W × 3 4-[2-(Dimethylamino)ethoxy]-~{N}-[[(3~{r})-5-(6- Methoxypyridin-2-Yl)-2,3-Dihydro-1,4-Benzodioxin- 3- Yl]methyl]benzamide PDB codes: 6fa2(A),
		18. Ligand: F8T × 3 [4-[[4-(3-Methoxyphenyl)phenyl]amino]phenyl]methyl- Dimethyl-Azanium PDB codes: 6gqw(A),
		19. Ligand: GTP × 3 Guanosine-5'-Triphosphate PDB codes: 5vpi(A), 5vq2(A), 6mnx(A).
		20. Ligand: PG4 × 3 Tetraethylene glycol PDB codes: 5vpy(A), 5vq1(A), 5wlb(A).
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Cluster 2 contains 2 ligand types

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Ligand		Description
		1. Ligand: GOL × 3 glycerin Glycerol PDB codes: 5v9u(A), 6b0y(A), 6mbu(A).
		2. Ligand: O5S × 1 2-[5-Chloro-2-Cyclopropyl-3-(5-Methoxy-3,4- Dihydroisoquinoline-2(1h)-Carbonyl)-7-Methyl-1h-Indol- 1-Yl]-N-(1-Propanoylazetidin-3-Yl)acetamide PDB code: 6p8z(A).

Cluster 3 contains 2 ligand types

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Ligand		Description
		1. Ligand: MES × 1 2-(N-Morpholino)-Ethanesulfonic acid PDB code: 6ob3(A).
		2. Ligand: SO4 × 1 Sulfate ion PDB code: 6pq3(A).

Cluster 4 contains 1 ligand type

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Ligand		Description
		1. Ligand: CIT × 3 citric acid Citric acid PDB codes: 6gog(A), 6gom(A), 6gqt(A).

Cluster 5 contains 2 ligand types

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Ligand		Description
		1. Ligand: GOL × 2 glycerin Glycerol PDB codes: 5us4(A), 6ark(A).
		2. Ligand: SO4 × 2 Sulfate ion PDB codes: 5mla(A), 5o2t(A).

Cluster 6 contains 3 ligand types

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Ligand		Description
_Ca		1. Metal: _CA × 8 PDB codes: 4luc(A), 4lv6(A), 5ufe(A), 5v6v(A), 5v9u(A), 6b0v(A), 6b0y(A), 6p8z(A).
		2. Ligand: ACT × 1 Acetate ion PDB code: 4dst(A).
		3. Ligand: EDO × 1 Ethane-1,2-Diol PDB code: 5yy1(A).