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Figure 1.
Fig. 1. RT-DNA tethering reaction. Chemistry of disulfide
bond formation between the side chain of an engineered cysteine
residue (blue) in helix H (gold) of RT to a thiol group in the
minor groove of DNA (activated as the mixed disulfide), which is
tethered to N2 of a dG (green) in the template:primer.
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