Figure 7.
Fig. 7. Effect of plasmin on FXa enzymatic
activity. FXa was
subjected to autoproteolysis ( ) or
cleavage by plasmin in the presence of PCPS and Ca^2+ ( ) or PCPS
and EDTA ( ) under the
conditions described in the legend to Fig. 3. At the times
indicated, FXa enzymatic activity was evaluated by a chromogenic
substrate assay (panel A, n = 3 ± S.D.) or in a one-stage
clotting assay (panel B, n = 2 ± S.E.), as described
under ``Experimental Procedures.''
enzymatic
activity. FXa 
) or
cleavage by plasmin in the presence of PCPS and Ca^2+ ( 
) or PCPS
and EDTA ( 
) under the
conditions described in the legend to Fig. 3. At the times
indicated, FXa enzymatic activity was evaluated by a chromogenic
substrate assay (panel A, n = 3 ± S.D.) or in a one-stage
clotting assay (panel B, n = 2 ± S.E.), as described
under ``Experimental Procedures.''