Figure 2.
Figure 2. The binding site of the nucleotide purine base in
rmCK2 .
a, The AMPPNP−rmCK2 complex
and b, the GMPPNP−rmCK2 complex.
The nucleotide molecules, the two magnesium ions and some
important water molecules are shown in green electron density
and the interdomain hinge region of the protein is shown in blue
electron density. All pieces of electron density are drawn from
(2F[o] - F[c]) density maps above a level of 1.2 .
Important hydrogen bonds are marked by magenta dotted lines with
donor-acceptor distances given in Å. For comparison, the
black nucleotide is GMPPNP in (a) and AMPPNP in (b). The
comparison shown is after the three-dimensional fit of the
protein matrices together with the most important water
molecules (large black balls) in its environment.
.
a, The AMPPNP−rmCK2 
complex
and b, the GMPPNP−rmCK2 
.
Important hydrogen bonds are marked by magenta dotted lines with
donor-acceptor distances given in Å. For comparison, the
black nucleotide is GMPPNP in (a) and AMPPNP in (b). The
comparison shown is after the three-dimensional fit of the
protein matrices together with the most important water
molecules (large black balls) in its environment.