|
Figure 1.
Figure 1. MERTK structure and mutations. a, The 19 coding
exons of human MERTK (GenBank AF260514−529) are depicted,
along with segments encoding various functional domains of the
protein: immunoglobulin-like (Ig-like), fibronectin-like
(FN-like), transmembrane (TM) and tyrosine kinase (TK). Vertical
arrows show the locations of identified mutations. Dashed lines
indicate that exons 1 and 19 include untranslated sequences that
are not depicted. b, Electropherograms demonstrating mutant
(top) and normal (bottom) sequences. An arrow indicates the
intron 10/exon 11 boundary.
|
