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Figure 5.
FIGURE 5. MARK2 dimer compared with MARK1 molecules E and
F. a, overlay of the MARK2 dimer (red) and molecules E and F of
MARK2 (green). b, close-up view of the activation segment
(magenta) and the surrounding elements in molecule E of MARK1
(dark colors), with nearby elements of molecule F shown in pale
colors. c, asin b but with molecule F (dark colors) in the same
orientation as molecule E in panel b; pale colors are for
elements belonging to molecule E. All superpositions by fit of
the C-lobes using helices E and F as reference structures.
Similar interactions as between molecules E/F exist between
MARK1 molecules A/B, C/D, and G/H.
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