Figure 4 - full size

Figure 4.
Fig. 4. . Schematic diagrams showing the intermolecular interactions between PETT inhibitors (in red) and the surrounding residues of HIV-1 RT for (a) PETT-1 and (b) PETT-2. Residues that contact the NNRTI with a minimum inter-atomic distance of 3.6 Å are shown in green, whereas other residues lining the binding pocket are shown in blue. The individual distances between the NNRTI and the protein atoms are shown as dashed lines (distances 3.3 Å in pink, 3.3 Å < distances 3.6 Å in light blue). Hydrogen bonds together with their distances are shown in black.