Figure 3 - full size

Figure 3.
Figure 3. Mouse nidogen-1 domain G2 is responsible for the major binding activity to perlecan fragment IG2-9. Solid-phase assays were carried out with immobilized IG2-9 and binding of soluble nidogen ligands was detected by antibodies specific for nidogen-1. These ligands were nidogen-1 ( open ) and its recombinant fragments NdI (0m), G2 ( triangle, open ) and NdIII ( ).