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Figure 3.
Fig. 3. Stereo representation of the structure of the
wild-type E. coli AspAT complexed with 2-methyl-L-aspartate
(16). The side chains of the six functionally important residues
mutated in this study are shown by full bonds (Asn34, Ile^37,
Ser139, Asn142, Asn297, and Val387). The coenzyme pyridoxal
5'-phosphate, the substrate analog, and the side chains of
Trp140 and Arg386 are also shown (open bonds). Asn297 belongs to
the other subunit of the dimer (asterisk).
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