Figure 2.
Figure 2 Close-up stereoview of the 3GalT
UDP-Gal-binding site. (A) Hg-UDP-Gal is shown in ball-and-stick
form and color coded depending on the nature of the atoms; the
Mn2+ ion is shown as a pink sphere. Amino acid side chains
interacting with Hg-UDP-Gal are shown in ball-and-stick form in
yellow. The acidic residues from the motifs D225VD227 and the
D316E317 are shown in ball-and-stick form in red. The four amino
acid side chains of 3GalT
residues at positions equivalent to the residues distinguishing
human A-GT from B-GT are shown in ball-and-stick form in blue.
(B) Stereoview of the electron density map (2F[o] - F[c], 1 )
of the Hg-UDP-Gal-binding site.
3GalT
UDP-Gal-binding site. (A) Hg-UDP-Gal is shown in ball-and-stick
form and color coded depending on the nature of the atoms; the
Mn2+ ion is shown as a pink sphere. Amino acid side chains
interacting with Hg-UDP-Gal are shown in ball-and-stick form in
yellow. The acidic residues from the motifs D225VD227 and the
D316E317 are shown in ball-and-stick form in red. The four amino
acid side chains of 
)
of the Hg-UDP-Gal-binding site.