Figure 1 - full size

Figure 1.
Fig. 1. a, overview of the Zif268 zinc finger-DNA complex. Only those side chains that make direct base contacts are shown. Finger one is red, fingers two and three are yellow, the DNA is blue, and the zinc ions are gray (adapted from Ref. 12). b, schematic diagram of the base contacts made by Zif268. Arrows indicate hydrogen bonds; dotted arrows represent hydrogen bonds with marginal geometry. Lines ending in filled circles represent van der Waals' interactions. The numbering scheme is the same as that used in papers describing the structure of the complex (11, 12) (adapted from Ref. 11).