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Figure 5.
Figure 5. Mapping of the most FA resistant mutants in EF-G.
A cartoon representation of the EF-G H573A structure is shown in
green. The side-chains of the six most FA resistant mutations
are shown in all-atom representation with carbon atoms coloured
blue. In decreasing order of FA resistance, these mutations are:
Phe90Leu, His458Tyr, Asp435Asn, Gln117Leu, Thr437Ile and
Gly453Ser.19 Most of these are located at or near the switch II
and domain III interface.
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