Figure 5 - full size

Figure 5.
Figure 5 Structural comparison of the zymogen and activated form. The upper and lower rows represent images rotated 180° with respect to each other, to show the channel in the active form. The electrostatic surface potential maps are shown in the center. The acidic and basic regions are colored red and blue, respectively. The arrow denotes a channel that opens on binding of a Ca^2+ ion in site 3. On the left and right are secondary structure images of the zymogen and the activated TGase 3 in the same orientations. The electrostatic potential, including calcium ions, has been mapped onto the surface plan from -15.0 kT (deep red) to +15.0 kT (deep blue).