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Figure 4.
Figure 4. Schematic diagram of the interactions of NLS
peptides with importin-a. The NLS backbone is shown as a black
line, with the side-chains shown as perpendicular lines
radiating from it. Individual Arm repeats of importin-a are
separated by tilted lines. Some importin-a side-chains
interacting with the NLS peptides are indicated: the invariant
asparagine residues in magenta, the invariant tryptophan
residues in green, and some nearby negatively charged residues
are shown in red. Y277 and R315 that interrupt the regular
asparagine and tryptophan array are also shown.
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