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Figure 4.
Figure 4. Detailed Views of the “Latch” and the
Crystallographic Dimer(A) Stereoview of a ribbon representation
of the folds of MIC-A (blue) and HLA-B27 (green) in the region
of helix 2b in the α2 domain highlighting the “latch.” The
side chains of the latch residue (Val-95 in MIC-A and Gly-100 in
HLA-B27) and the conserved disulfide bond (Cys-96/Cys-164) are
shown in ball-and-stick representation.(B and C) A view from the
side (B) and from the top (C) of the crystallographic dimer. The
two MIC-A monomers, one in red and the other in blue, are shown
as backbone ribbons. The ordered N-linked carbohydrate is shown
in ball-and-stick representation, and the crystallographic dyad
axis is indicated by the black oval. The C-termini of the two
monomers are colored yellow.
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