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Figure 4.
Figure 4 a, Topology of  -chain
(green) and  -chain
(red) C-terminal domains. The first residue in each segment of
secondary structure is numbered. b, Stereo depiction of
superposed C  backbone
structures from globular portions of -chains
(green) and -chains
(red); the numbers on the strands and letters on the helices
correspond to the secondary structure designations in Fig. 4. c,
GRASP representation of binding cavities of -chains
(left) and -chains
(right) showing charge distribution; red, negatively charged;
blue, positively charged^47. Domains have been reorientated to
show equivalent projections.
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