Figure 3 - full size

Figure 3. Figure 3. Hinge Motion in the C-Terminal Arch of Kapβ2 Stereo diagrams of the C-terminal arch (H9–H20) of chains A–D of unliganded Kapβ2 and substrate- and Ran-bound Kapβ2s superimposed at H9–H13 and drawn as spheres at the geometric center of each HEAT repeat. The hinge axes that rotate unliganded Kapβ2 with respect to substrate- and Ran-bound Kapβ2s are in pink and red, respectively.