|
Figure 3.
Figure 3. The recruitment-peptide-binding site of the
phospho-CDK2 -cyclin A3 complex. a, Diagram showing residues
RRLFGE from the recruitment peptide of p107 bound at the
hydrophobic site on cyclin A3, making contacts with residues
from successive turns of the 1
and 3
helices. The view, which is rotated ~90° from that shown in Fig.
2, shows the complete fold of the cyclin box. b, Similar view of
the equivalent residues from the phospho-CDK2 -cyclin A3
-p27^KIP1 complex (coordinates IJSU from the PDB^25).
|