Figure 2 - full size

Figure 2.
FIG. 2. Stereo pairs of surface rendered three-dimensional reconstructions of unlabeled EV12 virions (A) and DAF[34]-labeled virions (B). Isosurfaces of these reconstructions are merged and rendered in their respective color schemes to highlight the differences in density attributed to the two SCR domain fragment of DAF (C). A low resolution representation of EV7 bound to DAF[1234], derived from PDB code 1M11 [PDB] (30), highlights the differently oriented densities in these two complexes (D). In this model the densities of two copies of DAF[1234] are superimposed, laying across the virion 2-fold symmetry axes, giving rise to a hybrid density representing the two possible positions for the molecule. A radial depth-cue color scheme is used to indicate distance from the center of the virion (see the key).